期刊名：Non-Coding RNA

期刊链接：https://www.mdpi.com/journal/ncrna

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此类别系统覆盖非编码RNA（microRNA、circRNA、lncRNA、小RNA及外泌体RNA）在基础生物学、疾病机制与临床转化中的研究进展。内容涉及肿瘤无创诊断与预后（结直肠癌miRNA签名、血液肿瘤外泌体miRNA、唾液ncRNA用于口腔癌检测）、骨代谢调控（miRNA调控成骨与破骨分化）、宿主–病原体互作（细菌小RNA调控生存与毒力）、植物生长与胁迫响应，以及精子小非编码RNA图谱、银屑病lncRNA机制、乳腺癌干细胞血管生成拟态调控等。机制层面涵盖经典基因沉默、circRNA–mRNA直接结合、Argonaute互作组、ncRNA结构–功能关系及H?S与ncRNA交叉调控；技术层面包括低浓度血浆miRNA文库优化、结构预测方法学及食物来源miRNA的功能研究。无论聚焦基础机制还是临床标志物与治疗靶点，本文献清单提供了从分子事件到疾病转化的多尺度视角。

1. A miRNA Signature for Non-Invasive Colorectal Cancer Diagnosis in Morocco: miR-21, miR-29a and miR-92a

摩洛哥非侵入性结直肠癌诊断的miRNA标志物：miR-21、miR-29a和miR-92a

https://www.mdpi.com/2311-553X/11/2/26

Fathi, S.; Aazzane, O.; Guendaoui, S.; Tawfiq, N.; Sahraoui, S.; Guessous, F.; Karkouri, M. A miRNA Signature for Non-Invasive Colorectal Cancer Diagnosis in Morocco: miR-21, miR-29a and miR-92a. Non-Coding RNA 2025, 11, 26. https://doi.org/10.3390/ncrna11020026

2. Direct circRNA-mRNA Binding Controls mRNA Fate: A New Mechanism for circRNAs

直接的circRNA-mRNA结合调控mRNA命运：circRNA的新机制

https://www.mdpi.com/2311-553X/11/4/53

Garraffo, R.; Beltran Nebot, M. Direct circRNA-mRNA Binding Controls mRNA Fate: A New Mechanism for circRNAs. Non-Coding RNA 2025, 11, 53. https://doi.org/10.3390/ncrna11040053

3. Tiny but Mighty: Small RNAs—The Micromanagers of Bacterial Survival, Virulence, and Host–Pathogen Interactions

微小却强大：Small RNAs——细菌生存、致病性及宿主-病原体相互作用中的微观管理者

http://www.mdpi.com/2311-553X/11/3/36

Banerjee, R. Tiny but Mighty: Small RNAs—The Micromanagers of Bacterial Survival, Virulence, and Host–Pathogen Interactions. Non-Coding RNA 2025, 11, 36. https://doi.org/10.3390/ncrna11030036

4. Navigating the Landscape of Exosomal microRNAs: Charting Their Pivotal Role as Biomarkers in Hematological Malignancies

探索外泌体微小RNA的景观：揭示其在血液系统恶性肿瘤中作为生物标志物的关键作用

https://www.mdpi.com/2311-553X/11/5/64

Fazio, M.; Stagno, F.; Penna, G.; Mirabile, G.; Allegra, A. Navigating the Landscape of Exosomal microRNAs: Charting Their Pivotal Role as Biomarkers in Hematological Malignancies. Non-Coding RNA 2025, 11, 64. https://doi.org/10.3390/ncrna11050064

5. Decoding Salivary ncRNAomes as Novel Biomarkers for Oral Cancer Detection and Prognosis

解码唾液非编码RNA组作为口腔癌检测与预后的新生物标志物

https://www.mdpi.com/2311-553X/11/2/28

Das, S.; Basak, S.; Sarkar, S. Decoding Salivary ncRNAomes as Novel Biomarkers for Oral Cancer Detection and Prognosis. Non-Coding RNA 2025, 11, 28. https://doi.org/10.3390/ncrna11020028

6. The Role of microRNA in the Regulation of Differentiation and the Functionality of Osteoblasts, Osteoclasts, and Their Precursors in Osteoporosis

microRNA在骨质疏松症中成骨细胞、破骨细胞及其前体细胞分化与功能调控中的作用

https://www.mdpi.com/2311-553X/11/1/14

Yalaev, B.I.; Kaletnik, E.I.; Karpova, Y.S.; Belaya, Z.E.; Minniakhmetov, I.R.; Mokrysheva, N.G.; Khusainova, R.I. The Role of microRNA in the Regulation of Differentiation and the Functionality of Osteoblasts, Osteoclasts, and Their Precursors in Osteoporosis. Non-Coding RNA 2025, 11, 14. https://doi.org/10.3390/ncrna11010014

7. The Unpaved Road of Non-Coding RNA Structure–Function Relationships: Current Knowledge, Available Methodologies, and Future Trends

非编码RNA结构-功能关系的未铺就之路：当前知识、现有方法及未来趋势

https://www.mdpi.com/2311-553X/11/2/20

Leitão, A.L.; Enguita, F.J. The Unpaved Road of Non-Coding RNA Structure–Function Relationships: Current Knowledge, Available Methodologies, and Future Trends. Non-Coding RNA 2025, 11, 20. https://doi.org/10.3390/ncrna11020020

8. miRNA Library Preparation Optimisation for Low-Concentration and Low-Volume Paediatric Plasma Samples

针对低浓度、小体积儿科血浆样本的miRNA文库制备优化

https://www.mdpi.com/2311-553X/11/1/11

Rodgers, O.; Watson, C.; Waterfield, T. miRNA Library Preparation Optimisation for Low-Concentration and Low-Volume Paediatric Plasma Samples. Non-Coding RNA 2025, 11, 11. https://doi.org/10.3390/ncrna11010011

9. The Small Non-Coding RNA Profile of Human and Mouse Sperm

人类和小鼠精子的小型非编码RNA谱

https://www.mdpi.com/2311-553X/11/1/15

Yap, Y.S.; Patrizio, P.; Cimmino, L.; Sdrimas, K.; Telonis, A.G. The Small Non-Coding RNA Profile of Human and Mouse Sperm. Non-Coding RNA 2025, 11, 15. https://doi.org/10.3390/ncrna11010015

10. The Role of Long Non-Coding RNA in the Pathogenesis of Psoriasis

长链非编码RNA在银屑病发病机制中的作用

https://www.mdpi.com/2311-553X/11/1/7

Kieibowski, K.; Jedrasiak, A.; Bakinowska, E.; Pawlik, A. The Role of Long Non-Coding RNA in the Pathogenesis of Psoriasis. Non-Coding RNA 2025, 11, 7. https://doi.org/10.3390/ncrna11010007

11. Partners in Silencing: Decoding the Mammalian Argonaute Interactome

沉默中的伙伴：解读哺乳动物Argonaute互作图谱

https://www.mdpi.com/2311-553X/11/4/62

Narasimhan, S.; Erkeland, S.J. Partners in Silencing: Decoding the Mammalian Argonaute Interactome. Non-Coding RNA 2025, 11, 62. https://doi.org/10.3390/ncrna11040062

12. The Emerging Role of Non-Coding RNAs (ncRNAs) in Plant Growth, Development, and Stress Response Signaling

非编码RNA（ncRNAs）在植物生长、发育及应激响应信号传导中的新兴作用

https://www.mdpi.com/2311-553X/10/1/13

Yadav, A.; Mathan, J.; Dubey, A.K.; Singh, A. The Emerging Role of Non-Coding RNAs (ncRNAs) in Plant Growth, Development, and Stress Response Signaling. Non-Coding RNA 2024, 10, 13. https://doi.org/10.3390/ncrna10010013

13. MicroRNA Biogenesis, Gene Regulation Mechanisms, and Availability in Foods

微小RNA的生物合成、基因调控机制及其在食品中的可获得性

https://www.mdpi.com/2311-553X/10/5/52

de Mello, A.S.; Ferguson, B.S.; Shebs-Maurine, E.L.; Giotto, F.M. MicroRNA Biogenesis, Gene Regulation Mechanisms, and Availability in Foods. Non-Coding RNA 2024, 10, 52. https://doi.org/10.3390/ncrna10050052

14. Role of Hydrogen Sulfide in Oncological and Non-Oncological Disorders and Its Regulation by Non-Coding RNAs: A Comprehensive Review

硫化氢在肿瘤及非肿瘤性疾病中的作用及其由非编码RNA调控：全面综述

https://www.mdpi.com/2311-553X/10/1/7

Youness, R.A.; Habashy, D.A.; Khater, N.; Elsayed, K.; Dawoud, A.; Hakim, S.; Nafea, H.; Bourquin, C.; Abdel-Kader, R.M.; Gad, M.Z. Role of Hydrogen Sulfide in Oncological and Non-Oncological Disorders and Its Regulation by Non-Coding RNAs: A Comprehensive Review. Non-Coding RNA 2024, 10, 7. https://doi.org/10.3390/ncrna10010007

15. MicroRNA-204 Regulates Angiogenesis and Vasculogenic Mimicry in CD44+/CD24− Breast Cancer Stem-like Cells

MicroRNA-204调控CD44+/CD24−乳腺癌干细胞样细胞的血管生成和血管生成模拟

https://www.mdpi.com/2311-553X/10/1/14

Resendiz-Hernández, M.; García-Hernández, A.P.; Silva-Cázares, M.B.; Coronado-Uribe, R.; Hernández-de la Cruz, O.N.; Arriaga-Pizano, L.A.; Prieto-Chávez, J.L.; Salinas-Vera, Y.M.; Ibarra-Sierra, E.; Ortiz-Martínez, C.; et al. MicroRNA-204 Regulates Angiogenesis and Vasculogenic Mimicry in CD44+/CD24− Breast Cancer Stem-like Cells. Non-Coding RNA 2024, 10, 14. https://doi.org/10.3390/ncrna10010014

期刊介绍

主编：

Prof. Dr. Eleonora Leucci

Laboratory of RNA Cancer Biology, Department of Oncology, LKI, KU Leuven, 3000 Leuven, Belgium

Non-Coding RNA (ISSN 2311-553X) 是一个开放获取期刊，致力于为非编码RNA及其调控机制的研究提供高水平的学术交流平台。该期刊专注于非编码RNA的结构、功能与生物学特性，旨在推动科研人员在该领域的深入探索。期刊主要发表高质量的原创性研究论文和前沿综述，也欢迎对非编码RNA热点话题的评论，以推动学科的持续发展。

2025 Impact Factor：4.2

2025 CiteScore：6.1

Time to First Decision：30 Days

Acceptance to Publication：4 Days