期刊名：Journal of Developmental Biology

期刊主页：https://www.mdpi.com/journal/jdb

本期文章推荐主要关注生命发育过程中的关键基础机制研究，涵盖分子调控网络、细胞命运决定、遗传与表观遗传调控、干细胞分化、组织形态发生、再生修复以及生殖发育等重要研究方向。近年来，随着单细胞测序、基因编辑及多组学技术的快速发展，发育生物学领域不断深入解析信号通路、转录调控机制以及细胞间相互作用在组织形成、器官发育和功能维持中的核心作用。

1. Development-Associated Genes of the Epidermal Differentiation Complex (EDC)

表皮分化复合体中的发育相关基因

https://www.mdpi.com/2221-3759/12/1/4

Holthaus, K.B.; Eckhart, L. Development-Associated Genes of the Epidermal Differentiation Complex (EDC). J. Dev. Biol. 2024, 12, 4.

2. Canonical and Non-Canonical Wnt Signaling Generates Molecular and Cellular Asymmetries to Establish Embryonic Axes

经典和非经典Wnt信号通路建立胚胎体轴的不对称性

https://www.mdpi.com/2221-3759/12/3/20

Shi, D.-L. Canonical and Non-Canonical Wnt Signaling Generates Molecular and Cellular Asymmetries to Establish Embryonic Axes. J. Dev. Biol. 2024, 12, 20.

3. Established and Evolving Roles of the Multifunctional Non-POU Domain-Containing Octamer-Binding Protein (NonO) and Splicing Factor Proline- and Glutamine-Rich (SFPQ)

多功能非POU结构域含八聚体结合蛋白（NonO）和富含脯氨酸和谷氨酰胺的剪接因子（SFPQ）的既定和演变作用

https://www.mdpi.com/2221-3759/12/1/3

Yu, D.; Huang, C.-J.; Tucker, H.O. Established and Evolving Roles of the Multifunctional Non-POU Domain-Containing Octamer-Binding Protein (NonO) and Splicing Factor Proline- and Glutamine-Rich (SFPQ). J. Dev. Biol. 2024, 12, 3.

4.Getting to the Core: Exploring the Embryonic Development from Notochord to Nucleus Pulposus

直达核心：探索从脊索到髓核的胚胎发育

https://www.mdpi.com/2221-3759/12/3/18

Ambrosio, L.; Schol, J.; Ruiz-Fernández, C.; Tamagawa, S.; Joyce, K.; Nomura, A.; de Rinaldis, E.; Sakai, D.; Papalia, R.; Vadalà, G.; et al. Getting to the Core: Exploring the Embryonic Development from Notochord to Nucleus Pulposus. J. Dev. Biol. 2024, 12, 18.

5. Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation

平面细胞极性信号：细胞定向的协同调控

https://www.mdpi.com/2221-3759/12/2/12

Kacker, S.; Parsad, V.; Singh, N.; Hordiichuk, D.; Alvarez, S.; Gohar, M.; Kacker, A.; Rai, S.K. Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation. J. Dev. Biol. 2024, 12, 12.

6. Roles of the NR2F Family in the Development, Disease, and Cancer of the Lung

NR2F家族在肺发育、疾病和癌症中的功能

https://www.mdpi.com/2221-3759/12/3/24

Yang, J.; Sun, W.; Cui, G. Roles of the NR2F Family in the Development, Disease, and Cancer of the Lung. J. Dev. Biol. 2024, 12, 24.

7. Developmental Impacts of Epigenetics and Metabolism in COVID-19

COVID-19中表观遗传与代谢对发育的影响

https://www.mdpi.com/2221-3759/12/1/9

Naik, N.; Patel, M.; Sen, R. Developmental Impacts of Epigenetics and Metabolism in COVID-19. J. Dev. Biol. 2024, 12, 9.

8. CRISPR/Cas9-Targeted Myostatin Deletion Improves the Myogenic Differentiation Parameters for Muscle-Derived Stem Cells in Mice

CRISPR/Cas9靶向敲除肌生成抑制素（Myostatin）提升小鼠肌源性干细胞的肌生成分化能力

https://www.mdpi.com/2221-3759/13/1/5

Elashry, M.I.; Schneider, V.C.; Heimann, M.; Wenisch, S.; Arnhold, S. CRISPR/Cas9-Targeted Myostatin Deletion Improves the Myogenic Differentiation Parameters for Muscle-Derived Stem Cells in Mice. J. Dev. Biol. 2025, 13, 5.

9. Delayed Blastocyst Formation Reduces the Quality and Hatching Ability of Porcine Parthenogenetic Blastocysts by Increasing DNA Damage, Decreasing Cell Proliferation, and Altering Transcription Factor Expression Patterns

囊胚形成延迟通过诱导DNA 损伤、抑制细胞增殖并改变转录因子表达谱，削弱猪孤雌激活囊胚的发育质量和孵化能力

https://www.mdpi.com/2221-3759/12/4/26

Sun, L.; Wang, Y.; Yang, M.; Xu, Z.-J.; Miao, J.; Bai, Y.; Lin, T. Delayed Blastocyst Formation Reduces the Quality and Hatching Ability of Porcine Parthenogenetic Blastocysts by Increasing DNA Damage, Decreasing Cell Proliferation, and Altering Transcription Factor Expression Patterns. J. Dev. Biol. 2024, 12, 26.

10. Regeneration, Regengrow and Tissue Repair in Animals: Evolution Indicates That No Regeneration Occurs in Terrestrial Environments but Only Recovery Healing

动物中的再生、再生性生长与组织修复：进化研究表明陆地环境中不存在真正的再生，而仅有恢复性愈合

https://www.mdpi.com/2221-3759/13/1/2

Alibardi, L. Regeneration, Regengrow and Tissue Repair in Animals: Evolution Indicates That No Regeneration Occurs in Terrestrial Environments but Only Recovery Healing. J. Dev. Biol. 2025, 13, 2.

11. Genetics and Genomics of Gastroschisis, Elucidating a Potential Genetic Etiology for the Most Common Abdominal Defect: A Systematic Review

腹裂的遗传学和基因组学：阐明最常见腹部缺陷的潜在遗传病因

https://www.mdpi.com/2221-3759/12/4/34

Marquart, J.P.; Nie, Q.; Gonzalez, T.; Jelin, A.C.; Broeckel, U.; Wagner, A.J.; Reddi, H.V. Genetics and Genomics of Gastroschisis, Elucidating a Potential Genetic Etiology for the Most Common Abdominal Defect: A Systematic Review. J. Dev. Biol. 2024, 12, 34.

12. Emerging Contributions of Pluripotent Stem Cells to Reproductive Technologies in Veterinary Medicine

多能干细胞在兽医生殖技术中的新兴作用

https://www.mdpi.com/2221-3759/12/2/14

de Castro, R.C.F.; Buranello, T.W.; Recchia, K.; de Souza, A.F.; Pieri, N.C.G.; Bressan, F.F. Emerging Contributions of Pluripotent Stem Cells to Reproductive Technologies in Veterinary Medicine. J. Dev. Biol. 2024, 12, 14.

13. From Germ Cells to Implantation: The Role of Extracellular Vesicles

从生殖细胞到着床：细胞外囊泡的作用

https://www.mdpi.com/2221-3759/12/3/22

Fazzio, A.; Caponnetto, A.; Ferrara, C.; Purrello, M.; Di Pietro, C.; Battaglia, R. From Germ Cells to Implantation: The Role of Extracellular Vesicles. J. Dev. Biol. 2024, 12, 22.

14. Profilin and Non-Canonical Wnt Signaling: Coordinating Cytoskeletal Dynamics from Development to Disease

Profilin 与非经典 Wnt 信号通路：协调发育与疾病过程中的细胞骨架动态调控

https://www.mdpi.com/2221-3759/13/3/31

Alam, S.; Duncan, D.; Hasan, S. Profilin and Non-Canonical Wnt Signaling: Coordinating Cytoskeletal Dynamics from Development to Disease. J. Dev. Biol. 2025, 13, 31.

15. GLP-1-Mediated Pregnancy and Neonatal Complications in Mice

GLP-1介导的小鼠妊娠和新生儿并发症

https://www.mdpi.com/2221-3759/13/3/29

Ramamoorthy, R.; Carden, A.K.; Hussain, H.; Druyan, B.Z.; Chen, P.P.; Hajjar, R.; Fernandez, C.; Elumalai, N.; Rashed, A.B.; Young, K.; et al. GLP-1-Mediated Pregnancy and Neonatal Complications in Mice. J. Dev. Biol. 2025, 13, 29.

16.Effect of Cyclic Adenosine Monophosphate on Connexin 37 Expression in Sheep Cumulus-Oocyte Complexes

环磷酸腺苷调控绵羊卵丘-卵母细胞复合体中连接蛋白 37 表达的作用研究

https://www.mdpi.com/2221-3759/12/2/10

Zhao, M.; Subudeng, G.; Zhao, Y.; Hao, S.; Li, H. Effect of Cyclic Adenosine Monophosphate on Connexin 37 Expression in Sheep Cumulus-Oocyte Complexes. J. Dev. Biol. 2024, 12, 10.

17.Developmental Anomalies in Human Teeth: Odontoblastic Differentiation in Hamartomatous Calcifying Hyperplastic Dental Follicles Presenting with DSP, Nestin, and HES1

人类牙齿发育异常：错构性钙化增生性牙囊中成牙本质细胞分化及DSP、Nestin与HES1的表达

https://www.mdpi.com/2221-3759/12/1/7

Hasegawa, H.; Shimada, K.; Ochiai, T.; Okada, Y. Developmental Anomalies in Human Teeth: Odontoblastic Differentiation in Hamartomatous Calcifying Hyperplastic Dental Follicles Presenting with DSP, Nestin, and HES1. J. Dev. Biol. 2024, 12, 7.

18.Genes Related to Frontonasal Malformations Are Regulated by miR-338-5p, miR-653-5p, and miR-374-5p in O9-1 Cells

miR-338-5p、miR-653-5p 和 miR-374-5p 在 O9-1 细胞中调控前鼻部畸形相关基因的表达

https://www.mdpi.com/2221-3759/12/3/19

Iwaya, C.; Yu, S.; Iwata, J. Genes Related to Frontonasal Malformations Are Regulated by miR-338-5p, miR-653-5p, and miR-374-5p in O9-1 Cells. J. Dev. Biol. 2024, 12, 19.

19.Harderian Gland Development and Degeneration in the Fgf10-Deficient Heterozygous Mouse

Fgf10 缺陷杂合子小鼠的哈氏腺发育和退化

https://www.mdpi.com/2221-3759/12/2/16

Ikeda, S.; Sato, K.; Fujita, H.; Ono-Minagi, H.; Miyaishi, S.; Nohno, T.; Ohuchi, H. Harderian Gland Development and Degeneration in the Fgf10-Deficient Heterozygous Mouse. J. Dev. Biol. 2024, 12, 16.

期刊介绍

主编：Simon J. Conway,Indiana University School of Medicine, USA

Journal of Developmental Biology（ISSN 2221-3759）是一个国际化、经同行评审的开放获取期刊，由MDPI在线出版。发表的内容包括综述、研究论文以及关于多细胞生物在分子、细胞、组织、器官及整体水平发育过程的简报。期刊旨在鼓励研究者快速、无障碍地发表其新发现和研究构想，所有稿件须由同行评审。文章篇幅不设限制，作者需详尽提供实验细节以确保结果可重复。主题领域包括但不限于：发育机制与遗传调控；细胞命运决定与分化；胚胎发生与形态建成；组织和器官发育、模式形成；个体生长与发育节律；干细胞与再生生物学；性别决定与生殖发育；神经系统发育与轴突导向；心血管系统发育；免疫系统发育；进化发育生物学（Evo-Devo）；环境因素对发育过程的影响；发育异常、疾病模型与癌症发生机制等。已被ESCI (Web of Science), Scopus, PubMed, PMC等数据库收录。

2025 Impact Factor：2.4

2025 CiteScore：4.7