期刊名： Journal of Personalized Medicine

期刊主页：https://www.mdpi.com/journal/jpm

免疫系统是人体抵御病原体及维持内环境稳态的核心防线，其功能的异常或过度激活与炎症性疾病、肿瘤及自身免疫病的发病机制密切相关。通过识别不同患者独特的免疫表型、生物标志物及环境交互因素，个性化医学能实现定制化精准施治，提升临床治疗效果。本专题汇集了发表于 JPM 的系列研究，展示了银屑病机制解析、双特异性抗体应用及生物制剂真实世界疗效等前沿进展。研究涵盖了环境暴露、生活方式对免疫疾病的影响，以及细胞外囊泡等新型标志物的检测。这些成果为个性化医疗在免疫学领域的临床应用提供了研究依据。

1. Review: A Contemporary, Multifaced Insight into Psoriasis Pathogenesis

综述：关于银屑病发病机制的当代多维度见解

https://www.mdpi.com/2075-4426/14/5/535

Dascalu, R.C.; Barbulescu, A.L.; Stoica, L.E.; Dinescu, S.C.; Bita, C.E.; Popoviciu, H.V.; Ionescu, R.A.; Vreju, F.A. Review: A Contemporary, Multifaced Insight into Psoriasis Pathogenesis. J. Pers. Med. 2024, 14, 535.

2. The Development and Application of Bispecific Antibodies in B-Cell Non-Hodgkin Lymphoma

双特异性抗体在B细胞非霍奇金淋巴瘤中的研发与应用

https://www.mdpi.com/2075-4426/15/2/51

Sun, L.; Romancik, J.T. The Development and Application of Bispecific Antibodies in B-Cell Non-Hodgkin Lymphoma. J. Pers. Med. 2025, 15, 51.

3. Sinonasal Outcomes Obtained after 2 Years of Treatment with Benralizumab in Patients with Severe Eosinophilic Asthma and CRSwNP: A “Real-Life” Observational Study

本拉利珠单抗治疗伴有慢性鼻窦炎伴鼻息肉的重症嗜酸性粒细胞性哮喘患者两年后的鼻窦预后：一项“真实世界”观察性研究

https://www.mdpi.com/2075-4426/14/9/1014

De Corso, E.; Mele, D.A.; Rizzi, A.; Spanu, C.; Corbò, M.; Pisciottano, S.; Mastrapasqua, R.F.; Baroni, S.; Porru, D.P.; De Maio, G.; et al. Sinonasal Outcomes Obtained after 2 Years of Treatment with Benralizumab in Patients with Severe Eosinophilic Asthma and CRSwNP: A “Real-Life” Observational Study. J. Pers. Med. 2024, 14, 1014.

4. The Effects of Smoking, Alcohol, and Dietary Habits on the Progression and Management of Spondyloarthritis

吸烟、饮酒及饮食习惯对脊柱关节炎进展和管理的影响

https://www.mdpi.com/2075-4426/14/12/1114

Fatica, M.; Çela, E.; Ferraioli, M.; Costa, L.; Conigliaro, P.; Bergamini, A.; Caso, F.; Chimenti, M.S. The Effects of Smoking, Alcohol, and Dietary Habits on the Progression and Management of Spondyloarthritis. J. Pers. Med. 2024, 14, 1114.

5. Exploring the Immunological Role of the Microbial Composition of the Appendix and the Associated Risks of Appendectomies

探索阑尾微生物组成的免疫学作用及阑尾切除术的相关风险

https://www.mdpi.com/2075-4426/15/3/112

Islam, T.; Sagor, M.S.; Tamanna, N.T.; Bappy, M.K.I.; Danishuddin; Haque, M.A.; Lackner, M. Exploring the Immunological Role of the Microbial Composition of the Appendix and the Associated Risks of Appendectomies. J. Pers. Med. 2025, 15, 112.

6. The Relationship between Fine Particle Matter (PM2.5) Exposure and Upper Respiratory Tract Diseases

细颗粒物（PM2.5）暴露与上呼吸道疾病的相关性

https://www.mdpi.com/2075-4426/14/1/98

Zareba, L.; Piszczatowska, K.; Dzaman, K.; Soroczynska, K.; Motamedi, P.; Szczepański, M.J.; Ludwig, N. The Relationship between Fine Particle Matter (PM2.5) Exposure and Upper Respiratory Tract Diseases. J. Pers. Med. 2024, 14, 98.

7. Detection and Characterization of Extracellular Vesicles in Sputum Samples of COPD Patients

COPD患者诱导痰样本中细胞外囊泡的检测与表征

https://www.mdpi.com/2075-4426/14/8/820

Kotsiou, O.S.; Katsanaki, K.; Tsingene, A.; Papathanasiou, S.; Rouka, E.; Antonopoulos, D.; Gerogianni, I.; Balatsos, N.A.A.; Gourgoulianis, K.I.; Tsilioni, I. Detection and Characterization of Extracellular Vesicles in Sputum Samples of COPD Patients. J. Pers. Med. 2024, 14, 820.

8. The Effects of Mepolizumab on CRSwNP: Real-Life Evidence

美泊利珠单抗对慢性鼻窦炎伴鼻息肉的疗效：真实世界证据

https://www.mdpi.com/2075-4426/14/11/1112

Cantone, E.; Cassiano, B.; Pezzella, P.; Russo, M.B.; Detoraki, A., on behalf of Path2 Federico II Task Force. The Effects of Mepolizumab on CRSwNP: Real-Life Evidence. J. Pers. Med. 2024, 14, 1112.

期刊介绍

主编：Prof. Dr. Kenneth P.H. Pritzker, University of Toronto, Canada

JPM期刊致力于整合个性化医学的各个方面，推动该领域的研究与实践。期刊涵盖创新的临床前与转化科学研究、技术进展及临床应用，发表研究论文、综述、评论和通讯等多种类型文章，强调详实的实验与理论成果，注重研究可重复性。旨在搭建一个跨学科交流平台，汇聚学术研究者、临床医生、生物技术与制药企业、诊断专家、医疗从业者、伦理与监管机构以及政府部门，共同促进个性化医学的发展。

2025 CiteScore：6.0

Time to First Decision：25 Days

Acceptance to Publication：5.8 Days