期刊名：Bioengineering

期刊主页：https://www.mdpi.com/journal/bioengineering

水凝胶作为仿生细胞外基质的关键生物材料，近年来在组织工程与再生医学领域展现出广阔的应用前景。本专题精选发表于 Bioengineering 的系列研究，系统涵盖了多种功能化水凝胶体系的开发与应用：从口腔干细胞来源优化、壳聚糖基伤口敷料设计，到含BMP-2的肝素偶联纤维蛋白水凝胶用于骨修复，以及载外泌体、葛根素等功能成分的智能水凝胶在创面愈合中的应用。研究还融合了机器学习参数优化、3D生物打印、微流控等先进制造技术，并延伸至椎间盘退变、软骨再生、肝组织构建等复杂组织工程模型。这些工作共同展示了水凝胶材料从基础配方调控向智能化、多功能化发展的最新进展，为下一代组织修复策略提供了重要的理论依据与技术支撑。

1. Effects of Oral Cavity Stem Cell Sources and Serum-Free Cell Culture on Hydrogel Encapsulation of Mesenchymal Stem Cells for Bone Regeneration: An In Vitro Investigation

口腔干细胞来源及无血清细胞培养对间充质干细胞水凝胶包封用于骨再生的影响：一项体外研究

https://www.mdpi.com/2306-5354/11/1/59

2. In Vitro and In Vivo Evaluation of Chitosan/HPMC/Insulin Hydrogel for Wound Healing Applications

壳聚糖/羟丙甲纤维素/胰岛素水凝胶在体外 和 体内 伤口愈合应用中的评价

https://www.mdpi.com/2306-5354/11/2/168

3. Investigating the Effect of Processing and Material Parameters of Alginate Dialdehyde-Gelatin (ADA-GEL)-Based Hydrogels on Stiffness by XGB Machine Learning Model

利用XGB机器学习模型研究海藻酸二醛-明胶（ADA-GEL）基水凝胶的加工和材料参数对其刚度的影响

https://www.mdpi.com/2306-5354/11/5/415

4. Repair of Rat Calvarial Critical-Sized Defects Using Heparin-Conjugated Fibrin Hydrogel Containing BMP-2 and Adipose-Derived Pericytes

利用含BMP-2和脂肪来源周细胞的肝素偶联纤维蛋白水凝胶修复大鼠颅骨临界尺寸缺损

https://www.mdpi.com/2306-5354/11/5/437

5. An Exosome-Laden Hydrogel Wound Dressing That Can Be Point-of-Need Manufactured in Austere and Operational Environments

一种可在艰苦的作业环境中按需生产的载有外泌体的水凝胶伤口敷料

https://www.mdpi.com/2306-5354/11/8/804

6. Regenerative Outcomes of Combining siCOL1A2 Hydrogel with Acupuncture in a Rat Model of Chronic Intervertebral Disc Degeneration

siCOL1A2水凝胶联合针灸治疗大鼠慢性椎间盘退变的再生效果

https://www.mdpi.com/2306-5354/11/11/1066

7. Hydrogel-Enhanced Autologous Chondrocyte Implantation for Cartilage Regeneration—An Update on Preclinical Studies

水凝胶增强自体软骨细胞移植促进软骨再生——临床前研究最新进展

https://www.mdpi.com/2306-5354/11/11/1164

8. Open Microfluidic Cell Culture in Hydrogels Enabled by 3D-Printed Molds

3D打印模具助力水凝胶开放式微流控细胞培养

https://www.mdpi.com/2306-5354/12/2/102

9. Three-Dimensional Printing of Hydrogel as Skin Substitute and Comparative Evaluation of Melanin Production

利用三维打印技术制备水凝胶作为皮肤替代物，并比较其与黑色素生成量的关系

https://www.mdpi.com/2306-5354/12/3/270

10. Self-Healing Polymeric Puerarin Hydrogel Dressing Promotes Diabetic Wound Healing Through Synergistic Immunomodulation and Tissue-Regenerative Remodeling

自愈性聚合物葛根素水凝胶敷料通过协同免疫调节和组织再生重塑促进糖尿病伤口愈合

https://www.mdpi.com/2306-5354/12/4/427

11. An Injectable Kartogenin-Incorporated Hydrogel Supports Mesenchymal Stem Cells for Cartilage Tissue Engineering

一种可注射的含卡托吉宁的水凝胶支持间充质干细胞用于软骨组织工程

https://www.mdpi.com/2306-5354/12/5/434

12. Formulation and Evaluation of Licorice-Extract-Enhanced Chitosan, PVA, and Gelatin-Derived Hydrogels for Wound Dressing

甘草提取物增强型壳聚糖、聚乙烯醇和明胶衍生水凝胶的配制与评价及其在伤口敷料中的应用

https://www.mdpi.com/2306-5354/12/5/439

13. Engineering Multilayered Hepatic Cell Sheet Model Using Oxygen-Supplying MeHA/CPO Hydrogel

利用供氧型MeHA/CPO水凝胶构建多层肝细胞片模型

https://www.mdpi.com/2306-5354/12/10/1132

14. Overview of Magnetic Hydrogel Fabrication, Its Basic Characteristics, and Potential Uses in Biomedical Engineering

磁性水凝胶的制备、基本特性及其在生物医学工程中的潜在应用概述

https://www.mdpi.com/2306-5354/12/11/1142

15. Emerging Smart and Adaptive Hydrogels for Next-Generation Tissue Engineering

用于下一代组织工程的新型智能自适应水凝胶

https://www.mdpi.com/2306-5354/13/1/50

Bioengineering 期刊介绍

主编：Anthony Guiseppi-Elie, Anderson University, USA

主要发表生物医学工程及应用，生物过程和生物系统工程与应用，生物分子、细胞和组织工程及应用，以及生化工程与应用等相关领域的最新科学技术及应用。期刊已被PubMed、Scopus、SCIE (Web of Science) 等数据库收录。

2022 Impact Factor：4.6

2023 CiteScore：4.0

Time to First Decison：17.7 Days

Acceptance to Publication：3.6 Days