期刊名： Reproductive Medicine

期刊主页：https://www.mdpi.com/journal/reprodmed

高危妊娠是指因孕妇既往或合并内科疾病、妊娠并发症及胎盘或胎儿异常等因素，使母胎发生严重不良结局风险显著升高的妊娠状态。本专题遴选的15篇文献聚焦妊娠期高危因素及复杂并发症，如妊娠期糖尿病、妊娠相关急性肾损伤、急性脂肪肝及先兆子痫等，为优化临床监测与干预提供循证依据。若干病例报告呈现妊娠期埃文斯综合征、抗LGI1脑炎、宫角妊娠、放线菌感染以及持续性右脐静脉等罕见情形，强调多学科协作在诊治与妊娠结局平衡中的重要性。胎盘病理评分、脂联素及胎盘应激特征等研究从组织学和分子层面解析血栓形成倾向和氧化应激机制，有助于识别高危妊娠并探索潜在生物标志物。希望本专题为妊娠合并疾病及复杂妊娠的风险评估、个体化管理与机制研究提供丰富而前沿的参考，为临床实践与科研选题带来系统启发。

1. Acute Fatty Liver of Pregnancy

妊娠期急性脂肪肝：一种危及母胎安全的罕见但严重并发症

http://www.mdpi.com/2673-3897/5/4/25

White, A.; Nelson, D.B.; Cunningham, F.G. Acute Fatty Liver of Pregnancy. Reprod. Med. 2024, 5, 25.

2. Management of Evans’ Syndrome in Pregnancy: A Case Report and a Narrative Review

妊娠期埃文斯综合征的管理：病例报告及叙述性综述

http://www.mdpi.com/2673-3897/6/1/6

Fontana, G.; Fredi, M.; Nalli, C.; Orabona, R.; Guaragni, B.; Picciau, L.; Cancelli, V.; Andreoli, L.; Zatti, S.; Tincani, A. Management of Evans’ Syndrome in Pregnancy: A Case Report and a Narrative Review. Reprod. Med. 2025, 6, 6.

3. Diabetes Technology in Pregnant Women with Type 1 Diabetes—Distribution and Effects on Glycemic Regulation and Perinatal Outcomes

妊娠合并1型糖尿病的糖尿病技术应用：使用现状及其对血糖控制和围产期结局的影响

http://www.mdpi.com/2673-3897/5/1/2

Ghaur, S.Y.; Grinderslev, P.B.; Leth-Møller, M.; Ovesen, P.G.; Fuglsang, J.; Fisker, S.; McIntyre, H.D.; Kampmann, U. Diabetes Technology in Pregnant Women with Type 1 Diabetes—Distribution and Effects on Glycemic Regulation and Perinatal Outcomes. Reprod. Med. 2024, 5, 2.

4. Laparoscopic Management of Hemoperitoneum Due to a Cornual Pregnancy After an Ipsilateral Tubal Pregnancy: A Case Report

同侧输卵管妊娠后发生宫角妊娠致腹腔积血的腹腔镜处理：病例报告

http://www.mdpi.com/2673-3897/6/4/27

Tinelli, R.; Savasta, F.; Angioni, S.; Bogani, G.; Leo, L.; Messina, A.; Libretti, A. Laparoscopic Management of Hemoperitoneum Due to a Cornual Pregnancy After an Ipsilateral Tubal Pregnancy: A Case Report. Reprod. Med. 2025, 6, 27.

5. Adiponectin as a Biomarker of Preeclampsia: A Systematic Review

脂联素作为先兆子痫生物标志物：系统评价

http://www.mdpi.com/2673-3897/6/4/29

Carrilho, I.; Mariana, M.; Cairrao, E. Adiponectin as a Biomarker of Preeclampsia: A Systematic Review. Reprod. Med. 2025, 6, 29.

6. Incidentally Identified Basal Plate Myometrial Fibers and Hemorrhage Risk in the Subsequent Pregnancy

偶然发现的胎盘基底板肌层纤维与后续妊娠出血风险的关系

http://www.mdpi.com/2673-3897/6/2/10

Le, G.T.; Schauer, G.; Hung, Y.-Y.; Li, Y.; Ritterman-Weintraub, M.L.; Greenberg, M. Incidentally Identified Basal Plate Myometrial Fibers and Hemorrhage Risk in the Subsequent Pregnancy. Reprod. Med. 2025, 6, 10.

7. Cervical Cancer During Pregnancy: A Multidisciplinary Approach to a Complex Oncological Case

妊娠期宫颈癌：复杂肿瘤病例的多学科综合诊疗方案

http://www.mdpi.com/2673-3897/6/3/18

Vida, B.; Tóth, R.; Merkely, P.; Ács, N.; Novák, Z.; Balázs, B.; Madaras, L.; Bánhidy, F.; Tabányi, Á.; Keszthelyi, M.; Lintner, B. Cervical Cancer During Pregnancy: A Multidisciplinary Approach to a Complex Oncological Case. Reprod. Med. 2025, 6, 18.

8. Treatment of Type 1 Diabetes Mellitus During Pregnancy Using an Insulin Pump with an Advanced Hybrid Closed-Loop System: A Narrative Review

妊娠期1型糖尿病应用先进混合闭环胰岛素泵治疗：叙述性综述

http://www.mdpi.com/2673-3897/6/4/26

Dravecká, I. Treatment of Type 1 Diabetes Mellitus During Pregnancy Using an Insulin Pump with an Advanced Hybrid Closed-Loop System: A Narrative Review. Reprod. Med. 2025, 6, 26.

9. Exploring Pregnancy-Related Acute Kidney Injury: Risk Factors and Maternal Outcomes in High-Risk Women in Mwanza, Tanzania

妊娠相关急性肾损伤：坦桑尼亚姆万扎高危孕妇的风险因素及母体结局

http://www.mdpi.com/2673-3897/6/3/20

Bernard, K.; Mujuni, F.; Matovelo, D.; Ndaboine, E.; Kiritta, R.; Rudovick, L. Exploring Pregnancy-Related Acute Kidney Injury: Risk Factors and Maternal Outcomes in High-Risk Women in Mwanza, Tanzania. Reprod. Med. 2025, 6, 20.

10. Actinomyces in Pregnancy: A Rare and Silent Cause of Preterm Delivery—Case Report

妊娠期放线菌感染：导致早产的罕见且隐匿原因——病例报告

http://www.mdpi.com/2673-3897/6/1/7

Idaewor, P.; Ozua, P.; Jaiyesimi, R.A.K.; Al-Zawi, A.S.A. Actinomyces in Pregnancy: A Rare and Silent Cause of Preterm Delivery—Case Report. Reprod. Med. 2025, 6, 7.

11. New-Onset Anti-LGI1 Encephalitis in a Pregnant Woman

孕妇新发抗LGI1脑炎：妊娠期罕见神经免疫疾病病例

http://www.mdpi.com/2673-3897/6/1/5

Randall, B.; Schmitt, E.; McGraw, B.; Gloeb, D.; Blattner, M. New-Onset Anti-LGI1 Encephalitis in a Pregnant Woman. Reprod. Med. 2025, 6, 5.

12. Assessing Thrombophilic Risk via Placental Histopathology: A Comparative Scoring Analysis

通过胎盘组织病理学评估血栓形成倾向风险：比较评分分析

http://www.mdpi.com/2673-3897/6/4/32

Murvai, V.R.; Huniadi, A.; Galis, R.; Murvai, G.F.; Bernad, B.-C.; Silaghi, C.; Ghitea, T.C.; Rotar, I.C. Assessing Thrombophilic Risk via Placental Histopathology: A Comparative Scoring Analysis. Reprod. Med. 2025, 6, 32.

13. Hemodynamic Comparison of Inferior Vena Cava Collapsibility Index in Patients with Preeclampsia vs. Controls: A Pilot Study

先兆子痫患者与对照组下腔静脉塌陷指数的血流动力学比较：初步研究

http://www.mdpi.com/2673-3897/6/4/35

Sampson, R.; Mendez, P.R.; Kaul, V. Hemodynamic Comparison of Inferior Vena Cava Collapsibility Index in Patients with Preeclampsia vs. Controls: A Pilot Study. Reprod. Med. 2025, 6, 35.

14. The Placental Stress Code: Lymphocyte Proliferation, Immune and Metabolic Enzyme Shifts Reveal Oxidative Stress in Preeclampsia and Preeclampsia with Gestational Diabetes Mellitus

胎盘应激特征：淋巴细胞增殖及免疫与代谢酶变化揭示先兆子痫及合并妊娠期糖尿病先兆子痫中的氧化应激状态

http://www.mdpi.com/2673-3897/6/4/43

Balu, U.R.; Vasantharekha, R.; Priyanka, H.P.; Nair, R.S.; Mudgal, G.; Seetharaman, B. The Placental Stress Code: Lymphocyte Proliferation, Immune and Metabolic Enzyme Shifts Reveal Oxidative Stress in Preeclampsia and Preeclampsia with Gestational Diabetes Mellitus. Reprod. Med. 2025, 6, 43.

15. Persistent Right Umbilical Vein: Clinical Case and Literature Review

持续性右脐静脉：临床病例及文献综述

http://www.mdpi.com/2673-3897/6/4/36

Karakaite, D.; Volochovic, J. Persistent Right Umbilical Vein: Clinical Case and Literature Review. Reprod. Med. 2025, 6, 36.

期刊介绍

主编：Prof. Dr. Berthold Huppertz

Reproductive Medicine (ISSN 2673-3897) 是一个国际性开放获取英文学术期刊，聚焦妇产科学、生殖医学及生殖生物学领域的基础与临床研究。期刊涵盖母胎医学、妊娠与胚胎发育、生殖内分泌、生殖免疫、不孕不育、辅助生殖技术、生殖肿瘤学、男科学以及生殖相关疾病发病机制等多个研究方向，致力于促进生殖医学领域的学术交流与创新发展。

2025 Impact Factor：0.9

2025 CiteScore：1.7

Time to First Decision：21 Days

Acceptance to Publication：6 Days