直播时间：2025年6月24日（周二）20:00-21:30

 

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北京时间6月24日晚八点，iCANX Youth Talks第103期邀请到了宾夕法尼亚大学助理教授Yuanwen Jiang，辛辛那提大学助理教授Yeongin Kim，新加坡国立大学助理教授刘宇鑫担任主讲，华中科技大学助理教授陈书文担任研讨嘉宾，上海科技大学助理教授熊泽担任主持人，期待你一起加入这场知识盛宴。

 

【嘉宾介绍】

 

 

 

 

Yuanwen Jiang

 

宾夕法尼亚大学

 

Materials Strategies for Chronically Stable, High-Precision, Multimodal Bioelectronic Interfaces

 

【Abstract】

 

Bioelectronic medicine based on implantable and wearable devices can revolutionize how we manage diseases and dramatically improve healthcare outcomes. By continuously monitoring and analyzing key (patho)physiological signals, it allows for targeted and personalized treatment of diseases and conditions through precise modulation of cellular activities in a closed-loop manner. Despite the huge potential of bioelectronic medicine, existing medical devices still mostly relied on bulky and rigid electronic components, which severely limited their applications in the soft and dynamic tissue environment. In this talk, I will present our efforts on the exploration of rational design principles and engineering strategies to enable chronically stable, high-precision bioelectronic applications through fundamental material and device innovations.

 

基于可植入和可穿戴设备的生物电子医学能够彻底变革我们管理疾病的方式，并显著提升医疗成果。它通过持续监测和分析关键的（病理）生理信号，使得我们能够通过精确调节细胞活动以闭环方式对疾病和状况进行针对性和个性化的治疗。尽管生物电子医学具有巨大潜力，但现有的医疗设备仍然主要依赖于庞大且坚硬的电子元件，这严重限制了它们在柔软且动态的组织环境中的应用。在这次演讲中，我将介绍我们在探索合理的设计原则和工程策略方面的努力，通过基础材料和设备创新来实现长期稳定、高精度的生物电子应用。

 

【BIOGRAPHY】

 

Yuanwen Jiang joined the University of Pennsylvania as an Assistant Professor of Materials Science and Engineering in January 2023. His research has been focused on the design of bioelectronic materials and devices for medical applications. Dr. Jiang received his B.S. in Chemistry from Nanjing University in 2012 and his Ph.D. in Chemistry from the University of Chicago in 2018. Dr. Jiang conducted his postdoctoral research at Stanford University in the Department of Chemical Engineering. His previous works have received several scientific recognitions, including the ACS Young Investigator Symposium Award, IUPAC-SOLVAY International Award for Young Chemists, and Baxter Young Investigator Award.

 

Yuanwen Jiang于2023年1月加入宾夕法尼亚大学，担任材料科学与工程助理教授。他的研究专注于为医疗应用设计生物电子材料和设备。蒋博士于2012年在南京大学获得化学学士学位，2018年在芝加哥大学获得化学博士学位。蒋博士曾在斯坦福大学化学工程系进行博士后研究。他的先前工作获得了多项科学认可，包括美国化学会青年研究员研讨会奖、国际纯粹与应用化学联合会 - 索尔维国际青年化学家奖以及百特青年研究员奖。

 

 

Yeongin Kim

 

辛辛那提大学

 

Heterogeneous integration for chip-less wireless electronic skins and hemispherical organic image sensors

 

【ABSTRACT】

 

Heterogeneous integration and 3D integrated electronics/optoelectronics can lead to disruptive improvement in IoT devices. Conventionally, wireless electronic skins rely on rigid integrated circuit chips that compromise the overall flexibility and consume considerable power. I will talk about a chip-less wireless e-skin based on surface acoustic wave sensors made of freestanding ultrathin single-crystalline piezoelectric gallium nitride membranes. Surface acoustic wave–based e-skin offers highly sensitive, low-power, and long-term sensing of strain, ultraviolet light, and ion concentrations in sweat. Also, hemispherical image sensors based on organic semiconductors and photolithography processes are introduced. Our organic hemispherical image sensor array shows the best responsivity for similar dark currents among all the reported hemispherical image sensor arrays to date.

 

异质集成和三维集成电子/光电子技术可以为物联网设备带来颠覆性的改进。传统上，无线电子皮肤依赖于坚硬的集成电路芯片，这会损害整体的柔韧性并消耗相当大的功率。我将介绍一种基于表面声波传感器的无芯片无线电子皮肤，这种传感器由自由悬挂的超薄单晶压电氮化镓薄膜制成。基于表面声波的电子皮肤可实现对应变、紫外线和汗液中离子浓度的高灵敏度、低功耗和长期传感。此外，还将介绍基于有机半导体和光刻工艺的半球形图像传感器。我们的有机半球形图像传感器阵列在所有已报告的半球形图像传感器阵列中，在类似暗电流下展现出最佳的响应度。

 

【BIOGRAPHY】

 

Professor Yeongin Kim is an Assistant Professor in the Department of Electrical and Computer Engineering  and Department of Mechanical and Materials Engineering at the University of Cincinnati, where he has served since 2022. He holds a Ph.D. and M.S. in Electrical Engineering from Stanford University, following his undergraduate degree from Korea University. Prof. Kims research expertise lies in the field of organic and inorganic material growth and fabrication for flexible devices, wearable electronics, and optical sensors. His groundbreaking work over the past decade has resulted in 30 high-impact academic papers published in top journals, including Science and Nature, as well as four pending or granted US patents. In addition to his innovative research, Prof. Kim has actively contributed to the scientific community as a reviewer for prestigious journals, such as Nature and Science Advances, and through his role on the National Science Foundation (NSF) review panel. His notable achievements include first-author publications in Science in 2018 and 2022, showcasing flexible artificial nerves and chip-less wireless wearable sensors. Kims interdisciplinary work continues to push the boundaries of materials science and electronics for next-generation electronics.

 

Yeongin Kim 教授是美国辛辛那提大学电气与计算机工程系以及机械与材料工程系的助理教授，自 2022 年起任职。他拥有斯坦福大学电气工程专业的博士学位和硕士学位，此前在韩国大学获得了本科学位。Kim 教授的研究专长是用于柔性设备、可穿戴电子设备和光学传感器的有机和无机材料生长与制造。过去十年间，他开创性的工作成果包括在《科学》和《自然》等顶尖期刊上发表的 30 篇高影响力学术论文，以及四项待批或已授权的美国专利。除了创新性研究外，Kim 教授还积极参与科学界活动，担任《自然》和《科学进展》等知名期刊的审稿人，并在国家科学基金会（NSF）评审小组中担任成员。他的突出成就包括 2018 年和 2022 年以第一作者在《科学》上发表的论文，展示了柔性人工神经和无芯片无线可穿戴传感器。Kim 教授的跨学科工作不断推动材料科学和电子技术的发展，为下一代电子设备开辟新天地。

 

 

Yuxin Liu

 

新加坡国立大学

 

Rethink electrochemical interface with biological system

 

【ABSTRACT】

 

Bioelectronics engineered to share the softness, elasticity, and chemical acuity of living tissue enable truly continuous, realtime health monitoring. In this talk, I will present two such humancentric designs—one for the skin and one for the nerve tissue—demonstrating how electrochemical interfaces can unobtrusively and accurately harvest rich physiological signals from the body they seamlessly inhabit. First, I introduce a stretchable ionelectronic bilayer hydrogel for solidstate epidermal biomarker sensing. A clinical pilot study shows that the resulting solidstate epidermal biomarker profiles mirror venous blood chemistry and respond in real time to exercise and dietary challenges. I then describe tissuemimicking neural interfaces with unique electrochemical interface design for lowimpedance. Together, these advances illustrate how humancentric electrochemical interface can open universal routes to continuous biochemical sensing and precision neural interfacing.

 

具备与活体组织相当的柔软度、弹性及化学敏锐性的生物电子器件，使真正的连续、实时健康监测成为可能。在本次报告中，我将呈现两项以人体为中心的设计，一项面向皮肤、另一项面向神经组织，以展示电化学界面如何在无感存在的同时，精准捕获体内丰富的生理信号。首先，我将介绍一种可拉伸离子-电子双层水凝胶，用于固态表皮生物标志物检测。临床试点研究表明，所得固态表皮生物标志物谱与静脉血化学指标高度对应，并可实时响应运动与饮食挑战。随后，我将阐述一种仿组织神经接口，其独特的电化学界面设计带来极低阻抗。这些进展共同说明，以人为本的电化学界面可为持续生化传感与精准神经接口开辟通用路径。

 

【BIOGRAPHY】

 

Dr. Yuxin Liu is an Assistant Professor of Biomedical Engineering and a Principal Investigator at the Institute for Health Innovation & Technology (iHealthTech) and the N.1 Institute for Health at the National University of Singapore. He obtained his M.S. and Ph.D. in Bioengineering from Stanford University. Dr. Liu was awarded ICBME raising star, the NUS Presidential Young Professorship and was selected as one of the "Innovators Under 35" (Asia Pacific) by MIT Technology Review. His research interests include tissue-mimicking brain-machine interfaces and wearable electronics.

 

刘宇鑫博士现任新加坡国立大学（NUS）生物医学工程系助理教授，同时在健康创新与技术研究所（iHealthTech）及 N.1 健康研究院担任项目负责人。他在斯坦福大学获得生物工程学硕士和博士学位。他曾获 ICBME Rising Star 奖、国大校长青年教授（NUS Presidential Young Professorship），并入选《麻省理工科技评论》“35 岁以下创新者 （亚太区）”。其研究方向聚焦于仿组织脑机接口和可穿戴电子学。

 

【主持人】

 

 

Ze Xiong

 

上海科技大学

 

【研讨嘉宾】

 

 

Shuwen Chen

 

华中科技大学