直播时间：2025年4月22日（周二）20:00-21:30

直播平台：

科学网APP

https://weibo.com/l/wblive/p/show/1022:2321325158250613178539

（科学网微博直播间链接）

科学网微博

科学网视频号

北京时间4月22日晚八点，iCANX Youth Talks第94期邀请到了韩国中央大学助理教授Hanjun Ryu、韩国亚洲大学Jihye Kim担任主讲，新加坡国立大学助理教授Yiyuan（Harlon）Yang、韩国科学技术院教授Miso Kim担任研讨嘉宾，北京大学助理教授韩梦迪担任主持人，期待你一起加入这场知识盛宴。

【嘉宾介绍】

Hanjun Ryu

韩国中央大学

Wearable biomedical electronics for wound care

【Abstract】

Chronic wounds, particularly in diabetic patients, pose significant public health and economic challenges due to prolonged healing times and high risk of complications. Bioresorbable wearable systems for wound care offer promising solutions by enabling continuous treatment and monitoring. Here, we present a miniaturized, wireless, battery-free, and bioresorbable wearable electrotherapy platform that addresses key engineering barriers in chronic wound management. This system combines electrical stimulation to modulate inflammation, promote vasculogenesis, and accelerate epithelial migration with integrated sensing capabilities to monitor the healing process in real time. Using a splinted diabetic mouse wound model, we demonstrate accelerated wound closure and reliable tracking of healing progress through impedance changes. Additionally, the wearable platform incorporates spatio-temporal temperature sensing to provide continuous thermal mapping of the wound, offering insights into inflammatory responses and scar tissue formation. The bioresorbable nature of the materials allows for safe degradation within the body, eliminating the need for device retrieval and minimizing infection risks. Together, these features are able to establish a versatile, closed-loop, and patient-friendly wearable system for both active wound therapy and quantitative healing assessment. This approach will offer a powerful framework for advancing personalized wound care and enhancing clinical outcomes in chronic wound management.

慢性伤口，尤其是在糖尿病患者中，由于愈合时间长和并发症风险高，给公共卫生和经济带来了重大挑战。用于伤口护理的可生物吸收可穿戴系统通过实现持续治疗和监测，提供了有希望的解决方案。在此，我们介绍一种微型化、无线、无电池且可生物吸收的可穿戴电疗法平台，该平台解决了慢性伤口管理中的关键工程难题。该系统结合了电刺激以调节炎症、促进血管新生和加速上皮迁移，并集成了传感功能以实时监测愈合过程。通过使用夹板固定的糖尿病小鼠伤口模型，我们展示了加速的伤口闭合以及通过阻抗变化可靠地跟踪愈合进展。此外，该可穿戴平台还整合了时空温度传感功能，以提供伤口的连续热图，为炎症反应和瘢痕组织形成提供见解。材料的可生物吸收特性使其能够在体内安全降解，消除了设备回收的需要，并最大限度地减少了感染风险。这些功能共同建立了一个多功能、闭环且对患者友好的可穿戴系统，用于积极的伤口治疗和定量愈合评估。这种方法将为推进个性化伤口护理和改善慢性伤口管理的临床结果提供强大的框架。

【BIOGRAPHY】

Prof. Hanjun Ryu is an assistant professor in the department of advanced materials engineering at Chung-Ang University, South Korea. He obtained his BSE and Ph.D. in Advanced Materials Science and Engineering from Sungkyunkwan University (SKKU) in 2014 and 2019. After three years at Northwestern University as a postdoctoral researcher, he joined Chung-Ang University in 2022. He has published over 40 papers in numerous high-impact journals, including Science, Nature Electronics, Nature Communications, Science Advances, Advanced Materials, Energy & Environmental Science, etc. His recent research interests are pyroelectric, piezoelectric, and triboelectric effect-based applications, flexible 3D electronics for tissue-machine interface, and bioresorbable wearable/implantable biomedical devices.

Hanjun Ryu教授是韩国中央大学先进材料工程系的助理教授。他于2014年和2019年在成均馆大学获得先进材料科学与工程学士和博士学位。在西北大学完成三年博士后研究后，他于2022年加入中央大学。他在《科学》《自然·电子学》《自然·通讯》《科学进展》《先进材料》《能源与环境科学》等众多高影响力期刊上发表了40多篇论文。他的近期研究兴趣包括基于热释电、压电和摩擦电效应的应用，用于组织-机器界面的柔性3D电子设备，以及可生物吸收的可穿戴、植入式生物医学设备。

Jihye Kim

韩国亚洲大学

Real-time Bladder Function Monitoring System for Long-term Recovery Phase【ABSTRACT】

Partial cystectomy, one of the treatment methods for bladder-related diseases, requires a long recovery period of at least four weeks after surgery, and the degree of bladder recovery and bladder activity must be checked frequently during the recovery period. Here, we introduce a fully implantable bladder monitoring system for long-term recovery. The purpose of this system is for the physician or patient to continuously, ambulatory, and remotely monitor changes in bladder function at any time during the recovery phase following bladder partial cystectomy. The proposed bladder monitoring system has been validated to monitor bladder function in real-time over a long period of time in a rodent model and a non-human primate model that is phylogenetically similar to human. Our strategy will provide an improved translational tool to better predict the outcome of surgeries aimed at restoring bladder function.

膀胱部分切除术是治疗膀胱相关疾病的一种方法，术后需要至少四周的恢复期，并且在恢复期间需要频繁检查膀胱的恢复程度和膀胱活动。在此，我们介绍了一种完全可植入的膀胱监测系统，用于长期恢复。该系统旨在让医生或患者在膀胱部分切除术后恢复期间的任何时间，持续、便携且远程地监测膀胱功能的变化。我们提出的膀胱监测系统已在与人类亲缘关系较近的啮齿动物模型和非人灵长类动物模型中验证，能够长期实时监测膀胱功能。我们的策略将提供一种改进的转化工具，以更好地预测恢复膀胱功能的手术结果。

【BIOGRAPHY】

Jihye Kim is an assistant professor in the Advanced College of Bio-convergence Engineering at Ajou University, Republic of Korea. Her research focuses on wearable and implantable bioelectronics for real-time monitoring of physiological fluid signals. She advances digital healthcare through soft, integrated bioelectronics that enable continuous monitoring and intelligent diagnostics. She is the author of over 28 journal articles, which have collectively received more than 2,400 citations.

Jihye Kim是韩国亚洲大学高级生物融合工程学院的助理教授。她的研究专注于用于实时监测生理液体信号的可穿戴和可植入生物电子设备。她通过开发柔软、集成的生物电子设备推进数字医疗，这些设备能够实现持续监测和智能诊断。她发表了28篇以上的期刊文章，这些文章总共获得了超过2400次引用。

【主持人】

Mengdi Han

北京大学

【研讨嘉宾】

Yiyuan（Harlon）Yang

新加坡国立大学

Miso Kim

韩国科学技术院