首都医科大学附属北京口腔医院成立于1945年，八十载风雨兼程，医院始终秉承“严精勤谨，厚德博才”的院训精神，全心守护每一位患者的笑容，为健康中国战略贡献口腔人的力量。

为庆祝建院80周年，集中展示我国在“口腔医学”领域所取得的最新研究成果，‌Oral Science and Homeostatic Medicine (OSHM)‌特别策划并推出了“Celebrating the 80th Anniversary of Beijing Stomatological Hospital, Capital Medical University”纪念专刊。专刊不仅汇聚了国内在该领域的顶尖研究成果，更为国内外学者搭建了一个高水平的学术交流平台。

本期专刊共收录了‌13篇‌具有代表性的高水平研究论文，内容涵盖广泛，深度挖掘了口腔医学的多个关键方面。具体而言，专刊内容涵盖了miRNA与口腔鳞状细胞癌、基因组稳态与颅颌面畸形、中性粒细胞与牙周炎和阿尔茨海默病、骨下缺损的定量影像学指标、颅面器官发育中的各种细胞死亡类型、种植体表面改性处理与骨质疏松症、微波辐射与口腔健康‌、细胞外基质刚度与骨髓间充质干细胞成骨分化、昼夜节律稳态的生物标志物‌、机械力与矿物沉积和晶体转变、基因变异与牙齿发育不全、牙周病的精准诊断、上颌和下颌牙胚转录组学分析与基因表达等。

这些研究不仅展示了我国学者在口腔医学的最新研究成果，也为国际学术界的同仁提供了宝贵的参考和启示。我们诚挚地邀请广大科研工作者、临床医生及相关领域的专家学者关注本期专刊，共同为推动口腔医学的研究与实践贡献力量。让我们携手前行，在探索口腔医学的道路上不断取得新的突破！敬请期待并广泛关注！

REVIEWS

1.Genomic Homeostasis and Congenital Cranio-Maxillofacial Malformations.

Zhiyuan Pan, Jingya Li, Hongwei Wang, Guofen Lin, Xiaoyi Zhang, Jiewen Dai

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610008

2. The roles of different forms of cell death in the fate decision and morphogenesis of craniofacial organs.

Tan Tan, Huanan Zhang, Xuechun Li, Xiaoshan Wu

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610015

3.Neutrophils linking periodontitis and Alzheimers disease.

Juanjuan Li, Liangliang Liu, Xu Chang, Jing Zhang, Fu Wang

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610022

4.Dental implant surface modification for promoting peri-implant osseointegration in osteoporosis.

Boyu Liu, Xiaojie Chen, Shangyong Zuo, Yihong Chen, Hengrong Xiong, Zhiwei Peng, Ousheng Liu, Qian Peng

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610023

5.Effects and mechanisms of microwave radiation on oral health.

Jun Cui, Jingui Gu, Junji Xu

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610024

6.ECM stiffness-mediated regulation of glucose metabolism in MSCs osteogenic differentiation: mechanisms, intersections, and implications.

Hao Yan, Jian Zhou, Tingting Wu

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610025

7.Circadian rhythm homeostasis biomarkers: current landscape and emerging frontiers.

Shaorong Li, Changxin Zhang, Yuxuan Lin, Songlin Wang

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610028

8.Data-driven precision diagnosis of periodontal disease: from biological features analysis to clinical applications.

Haonan Song, Zhen Chai, Yiru Yu, Zhen Wang, Ang Li

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610031

ORINGINAL ARTICLE

1.MiR-145 affects cell cycles by inhibiting cyclin A2 and cyclin dependent kinase 6 in oral squamous cell carcinoma, a progression and prognostic biomarker. 

Hao Pan, Yuehong Wang, Xinna Bai, Binjie Liu, Hongzhi Quan, Qingwen Zeng, Jiajia Zeng, Qian Tang, Liqun Gu, Zhiyuan Deng, Zhigang Yao, Ousheng Liu, Zhangui Tang

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610002

2.The facilitating effects of mechanical forces on mineral deposition and crystal transition

Xinli Lv, Jiani Liu, Zijie Zhang, Jixiao Wang, Lan li, Yuxia Luan, Fulan Wei

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610027

3.Identification of two novel variants in homeodomain of MSX1 associated with oligodontia.

Ting Zeng, Xiuyou Wang, Li Xu, Xin Dong, Xili Qiu, Zhiyuan Deng, Saimin Pei, Rong Lei, Yuehong Wang, Ling Peng

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610029

4. Comparative transcriptomic analysis of human maxillary and mandibular tooth germs reveals discrepancies in gene expression patterns

Zhenni Zhao, Dongxiao Wu, Hanzhang Zhou, Zongshan Shen, Xiuge Gu, Wei Wei, Chuan Wu, Suwen Chen, Jinxuan Xia, Chunmei Zhang, Jingsong Wang, Xiaoshan Wu, Mengjie Han, Jinchu Liang, Ran Zhang, Songlin Wang

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610032

CASE REPORT

1.The radiographic measurement for infrabony defects by CBCT in periodontal regeneration: technical report. 

Xu Liu, Jianhui Han, Yingyi Chen, Jingchao Hu, Yi Liu

Oral Science and Homeostatic Medicine, 2025,

https://doi.org/10.26599/OSHM.2025.9610019