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Cells新增216篇ESI（Essential Science Indicators）高被引论文，4篇热点论文，学术影响力持续提升，欢迎学界关注！

期刊名：Cells

期刊主页：https://www.mdpi.com/journal/cells

ESI高被引论文（Highly Cited Paper）指同一出版年、同一ESI学科内所有发表论文按被引频次降序排列后，被引频次跻身该领域前1%的论文。

ESI热点论文 （Hot Papers）：同一ESI学科近两年发表的论文，依据近两个月被引频次，入选该领域前0.1%的论文。

Cells (ISSN: 2073-4409) 是MDPI 旗下-细胞生物学领域的一本国际开放期刊 （https://www.mdpi.com/journal/cells）。2024 年期刊获得新的影响因子（IF）为 5.2，5年IF为6.1，JCR分区2区；最新 CiteScore达 10.5。该期刊目前已被多个国际权威数据库收录，包括科学引文索引扩展版（SCIE，Web of Science 核心合集）、PubMed、Scopus、医学文献分析和检索系统（MEDLINE）、PubMed Central（PMC）及化学文摘 plus 版 / 科学发现者（CAPlus/SciFinder）等。

2025年10月ESI高被引论文

1 Innovation at the Intersection: Emerging Translational Research in Neurology and Psychiatry

Tanaka, Masaru; Battaglia, Simone; Gimenez-Llort, Lydia; Chen, Chong; Hepsomali, Piril; Avenanti, Alessio; Vecsei, Laszlo

http://dx.doi.org/10.3390/cells13100790

2 Border Control: The Role of the Microbiome in Regulating Epithelial Barrier Function

Schreiber, Fernanda; Balas, Iulia; Robinson, Matthew J.; Bakdash, Ghaith

http://dx.doi.org/10.3390/cells13060477

3 Extracellular Matrix Cues Regulate Mechanosensing and Mechanotransduction of Cancer Cells

Mierke, Claudia Tanja

http://dx.doi.org/10.3390/cells13010096

4 Heme Oxgenase-1, a Cardinal Modulator of Regulated Cell Death and Inflammation

Ryter, Stefan W.

http://dx.doi.org/10.3390/cells10030515

5 Future Directions in the Treatment of Osteosarcoma

Smrke, Alannah; Anderson, Peter M.; Gulia, Ashish; Gennatas, Spyridon; Huang, Paul H.; Jones, Robin L.

http://dx.doi.org/10.3390/cells10010172

6 miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis

Condrat, Carmen Elena; Thompson, Dana Claudia; Barbu, Madalina Gabriela; Bugnar, Oana Larisa; Boboc, Andreea; Cretoiu, Dragos; Suciu, Nicolae; Cretoiu, Sanda Maria; Voinea, Silviu Cristian

http://dx.doi.org/10.3390/cells9020276

7 Role of Angiopoietin-2 in Vascular Physiology and Pathophysiology

Akwii, Racheal G.; Sajib, Md S.; Zahra, Fatema T.; Mikelis, Constantinos M.

http://dx.doi.org/10.3390/cells8050471

8 Angiogenesis in Glioblastoma-Treatment Approaches

Nowacka, Agnieszka; Sniegocki, Maciej; Smuczynski, Wojciech; Bozilow, Dominika; Ziolkowska, Ewa

http://dx.doi.org/10.3390/cells14060407

9 Role of Inflammatory Mechanisms in Major Depressive Disorder: From Etiology to Potential Pharmacological Targets

Kouba, Bruna R.; Borba, Laura de Araujo; de Souza, Pedro Borges; Gil-Mohapel, Joana; Rodrigues, Ana Lucia S.

http://dx.doi.org/10.3390/cells13050423

10 Modulation of NRF2/KEAP1 Signaling in Preeclampsia

Tossetta, Giovanni; Fantone, Sonia; Piani, Federica; Crescimanno, Caterina; Ciavattini, Andrea; Giannubilo, Stefano Raffaele; Marzioni, Daniela

http://dx.doi.org/10.3390/cells12111545

11 Macrophages, Chronic Inflammation, and Insulin Resistance

Li, He; Meng, Ya; He, Shuwang; Tan, Xiaochuan; Zhang, Yujia; Zhang, Xiuli; Wang, Lulu; Zheng, Wensheng

http://dx.doi.org/10.3390/cells11193001

12 Immunotherapy, Inflammation and Colorectal Cancer

Lichtenstern, Charles Robert; Ngu, Rachael Katie; Shalapour, Shabnam; Karin, Michael

http://dx.doi.org/10.3390/cells9030618

13 The Role of IL-6 in Cancer Cell Invasiveness and Metastasis-Overview and Therapeutic Opportunities

Raskova, Magdalena; Lacina, Lukas; Kejik, Zdenek; Venhauerova, Anna; Skalickova, Marketa; Kolai, Michal; Jakubek, Milan; Rosel, Daniel; Smetana, Karel Jr Jr; Brabek, Jan

http://dx.doi.org/10.3390/cells11223698

14 Autophagy: A Key Regulator of Homeostasis and Disease: An Overview of Molecular Mechanisms and Modulators

Gomez-Virgilio, Laura; Silva-Lucero, Maria-del-Carmen; Flores-Morelos, Diego-Salvador; Gallardo-Nieto, Jazmin; Lopez-Toledo, Gustavo; Abarca-Fernandez, Arminda-Mercedes; Zacapala-Gomez, Ana-Elvira; Luna-Munoz, Jose; Montiel-Sosa, Francisco; Soto-Rojas, Luis O.; Pacheco-Herrero, Mar; Cardenas-Aguayo, Maria-del-Carmen

http://dx.doi.org/10.3390/cells11152262

15 Research Advances in Cadmium Uptake, Transport and Resistance in Rice (Oryza sativa L.)

Zhang, Jialiang; Zhu, Yanchun; Yu, Lijuan; Yang, Meng; Zou, Xiao; Yin, Changxi; Lin, Yongjun

http://dx.doi.org/10.3390/cells11030569

16 The Role of Macrophages in the Development of Acute and Chronic Inflammatory Lung Diseases

Lee, Jae-Won; Chun, Wanjoo; Lee, Hee Jae; Min, Jae-Hong; Kim, Seong-Man; Seo, Ji-Yun; Ahn, Kyung-Seop; Oh, Sei-Ryang

http://dx.doi.org/10.3390/cells10040897

17 Macrophages in Lung Injury, Repair, and Fibrosis

Cheng, Peiyong; Li, Shuangyan; Chen, Huaiyong

http://dx.doi.org/10.3390/cells10020436

18 Cyclin D1 in Cancer: A Molecular Connection for Cell Cycle Control, Adhesion and Invasion in Tumor and Stroma

Montalto, Francesca Ida; De Amicis, Francesca

http://dx.doi.org/10.3390/cells9122648

19 Microglia: Agents of the CNS Pro-Inflammatory Response

Rodriguez-Gomez, Jose A.; Kavanagh, Edel; Engskog-Vlachos, Pinelopi; Engskog, Mikael K. R.; Herrera, Antonio J.; Espinosa-Oliva, Ana M.; Joseph, Bertrand; Hajji, Nabil; Venero, Jose L.; Burguillos, Miguel A.

http://dx.doi.org/10.3390/cells9071717

20 Structure and Function of Human Matrix Metalloproteinases

Laronha, Helena; Caldeira, Jorge

http://dx.doi.org/10.3390/cells9051076

21 The Hemocompatibility of Nanoparticles: A Review of Cell-Nanoparticle Interactions and Hemostasis

de la Harpe, Kara M.; Kondiah, Pierre P. D.; Choonara, Yahya E.; Marimuthu, Thashree; du Toit, Lisa C.; Pillay, Viness

http://dx.doi.org/10.3390/cells8101209

22 Current Strategies for Exosome Cargo Loading and Targeting Delivery

Zeng, Haifeng; Guo, Shaoshen; Ren, Xuancheng; Wu, Zhenkun; Liu, Shuwen; Yao, Xingang

http://dx.doi.org/10.3390/cells12101416

23 Cancer Spheroids and Organoids as Novel Tools for Research and Therapy: State of the Art and Challenges to Guide Precision Medicine

El Harane, Sanae; Zidi, Bochra; El Harane, Nadia; Krause, Karl-Heinz; Matthes, Thomas; Preynat-Seauve, Olivier

http://dx.doi.org/10.3390/cells12071001

24 Various AAV Serotypes and Their Applications in Gene Therapy: An Overview

Issa, Shaza S.; Shaimardanova, Alisa A.; Solovyeva, Valeriya V.; Rizvanov, Albert A.

http://dx.doi.org/10.3390/cells12050785

25 Gut Microbiota-Derived Tryptophan Metabolites Maintain Gut and Systemic Homeostasis

Su, Xiaomin; Gao, Yunhuan; Yang, Rongcun

http://dx.doi.org/10.3390/cells11152296

26 Regulation and Dysregulation of Endothelial Permeability during Systemic Inflammation

Hellenthal, Katharina E. M.; Brabenec, Laura; Wagner, Nana-Maria

http://dx.doi.org/10.3390/cells11121935

27 Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation

Schiliro, Chelsea; Firestein, Bonnie L.

http://dx.doi.org/10.3390/cells10051056

28 Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration

Ha, Dae Hyun; Kim, Hyun-keun; Lee, Joon; Kwon, Hyuck Hoon; Park, Gyeong-Hun; Yang, Steve Hoseong; Jung, Jae Yoon; Choi, Hosung; Lee, Jun Ho; Sung, Sumi; Yi, Yong Weon; Cho, Byong Seung

http://dx.doi.org/10.3390/cells9051157

29 The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer

Hammouda, Manel B.; Ford, Amy E.; Liu, Yuan; Zhang, Jennifer Y.

http://dx.doi.org/10.3390/cells9040857

30 Cysteine Cathepsins and Their Extracellular Roles: Shaping the Microenvironment

Vidak, Eva; Javorsek, Urban; Vizovisek, Matej; Turk, Boris

http://dx.doi.org/10.3390/cells8030264

31 Pathogenesis of DJ-1/PARK7-Mediated Parkinsons Disease

Skou, Line Duborg; Johansen, Steffi Krudt; Okarmus, Justyna; Meyer, Morten

http://dx.doi.org/10.3390/cells13040296

32 Pathogenesis Underlying Neurological Manifestations of Long COVID Syndrome and Potential Therapeutics

Leng, Albert; Shah, Manuj; Ahmad, Syed Ameen; Premraj, Lavienraj; Wildi, Karin; Li Bassi, Gianluigi; Pardo, Carlos A.; Choi, Alex; Cho, Sung-Min

http://dx.doi.org/10.3390/cells12050816

33 PI3K/AKT/mTOR-Targeted Therapy for Breast Cancer

Zhu, Kunrui; Wu, Yanqi; He, Ping; Fan, Yu; Zhong, Xiaorong; Zheng, Hong; Luo, Ting

http://dx.doi.org/10.3390/cells11162508

34 Advanced Glycation End-Products (AGEs): Formation, Chemistry, Classification, Receptors, and Diseases Related to AGEs

Twarda-Clapa, Aleksandra; Olczak, Aleksandra; Bialkowska, Aneta M.; Koziolkiewicz, Maria

http://dx.doi.org/10.3390/cells11081312

35 Beyond Activation: Characterizing Microglial Functional Phenotypes

Lier, Julia; Streit, Wolfgang J.; Bechmann, Ingo

http://dx.doi.org/10.3390/cells10092236

36 Dopamine: The Neuromodulator of Long-Term Synaptic Plasticity, Reward and Movement Control

Speranza, Luisa; di Porzio, Umberto; Viggiano, Davide; de Donato, Antonio; Volpicelli, Floriana

http://dx.doi.org/10.3390/cells10040735

37 Biomarkers in Hepatocellular Carcinoma: Diagnosis, Prognosis and Treatment Response Assessment

Pinero, Federico; Dirchwolf, Melisa; Pessoa, Mario G.

http://dx.doi.org/10.3390/cells9061370

38 The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

Loh, Chin-Yap; Chai, Jian Yi; Tang, Ting Fang; Wong, Won Fen; Sethi, Gautam; Shanmugam, Muthu Kumaraswamy; Chong, Pei Pei; Looi, Chung Yeng

http://dx.doi.org/10.3390/cells8101118

39 Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

Doyle, Laura M.; Wang, Michael Zhuo

http://dx.doi.org/10.3390/cells8070727

40 Green-Synthesized Silver and Selenium Nanoparticles Using Berberine: A Comparative Assessment of In Vitro Anticancer Potential on Human Hepatocellular Carcinoma Cell Line (HepG2)

Khaled, Azza M.; Othman, Mohamed S.; Obeidat, Sofian T.; Aleid, Ghada M.; Aboelnaga, Shimaa M.; Fehaid, Alaa; Hathout, Heba M. R.; Bakkar, Ashraf A.; Moneim, Ahmed E. Abdel; El-Garawani, Islam M.; Morsi, Dalia S.

http://dx.doi.org/10.3390/cells13030287

41 Innate Immune Cell Death in Neuroinflammation and Alzheimers Disease

Rajesh, Yetirajam; Kanneganti, Thirumala-Devi

http://dx.doi.org/10.3390/cells11121885

42 Significance of Interleukin (IL)-4 and IL-13 in Inflammatory Arthritis

Iwaszko, Milena; Bialy, Sylwia; Bogunia-Kubik, Katarzyna

http://dx.doi.org/10.3390/cells10113000

43 Cellular and Molecular Mechanisms Underlying Liver Fibrosis Regression

Caligiuri, Alessandra; Gentilini, Alessandra; Pastore, Mirella; Gitto, Stefano; Marra, Fabio

http://dx.doi.org/10.3390/cells10102759

44 Hypoxia, Metabolic Reprogramming, and Drug Resistance in Liver Cancer

Bao, Macus Hao-Ran; Wong, Carmen Chak-Lui

http://dx.doi.org/10.3390/cells10071715

45 Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease

Salvi, Pooja S.; Cowles, Robert A.

http://dx.doi.org/10.3390/cells10071775

46 Cancer Metabolism: Phenotype, Signaling and Therapeutic Targets

Park, Jae Hyung; Pyun, Woo Yang; Park, Hyun Woo

http://dx.doi.org/10.3390/cells9102308

47 The Role of Tumor-Associated Macrophages in the Progression and Chemoresistance of Ovarian Cancer

Nowak, Marek; Klink, Magdalena

http://dx.doi.org/10.3390/cells9051299

48 Current Advancements in Spinal Cord Injury Research-Glial Scar Formation and Neural Regeneration

Clifford, Tanner; Finkel, Zachary; Rodriguez, Brianna; Joseph, Adelina; Cai, Li

http://dx.doi.org/10.3390/cells12060853

49 Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health

Mazziotta, Chiara; Tognon, Mauro; Martini, Fernanda; Torreggiani, Elena; Rotondo, John Charles

http://dx.doi.org/10.3390/cells12010184

50 The Role of Oxidative Stress in Atherosclerosis

Batty, Matthew; Bennett, Martin R.; Yu, Emma

http://dx.doi.org/10.3390/cells11233843

51 Sarcoidosis: A Clinical Overview from Symptoms to Diagnosis

Seve, Pascal; Pacheco, Yves; Durupt, Francois; Jamilloux, Yvan; Gerfaud-Valentin, Mathieu; Isaac, Sylvie; Boussel, Loic; Calender, Alain; Androdias, Geraldine; Valeyre, Dominique; El Jammal, Thomas

http://dx.doi.org/10.3390/cells10040766

52 Cellular and Molecular Differences between HFpEF and HFrEF: A Step Ahead in an Improved Pathological Understanding

Simmonds, Steven J.; Cuijpers, Ilona; Heymans, Stephane; Jones, Elizabeth A. V.

http://dx.doi.org/10.3390/cells9010242

53 Long Non-Coding RNA in the Pathogenesis of Cancers

Chi, Yujing; Wang, Di; Wang, Junpei; Yu, Weidong; Yang, Jichun

http://dx.doi.org/10.3390/cells8091015

54 Keratin 6, 16 and 17-Critical Barrier Alarmin Molecules in Skin Wounds and Psoriasis

Zhang, Xiaowei; Yin, Meimei; Zhang, Ling-juan

http://dx.doi.org/10.3390/cells8080807

55 Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid

Busatto, Sara; Vilanilam, George; Ticer, Taylor; Lin, Wen-Lang; Dickson, Dennis W.; Shapiro, Shane; Bergese, Paolo; Wolfram, Joy

http://dx.doi.org/10.3390/cells7120273

56 Multiple Roles of the Small GTPase Rab7

Guerra, Flora; Bucci, Cecilia

http://dx.doi.org/10.3390/cells5030034

57 Role of the Skin Immune System in Wound Healing

Cioce, Angela; Cavani, Andrea; Cattani, Caterina; Scopelliti, Fernanda

http://dx.doi.org/10.3390/cells13070624

58 TNF-Related Apoptosis-Inducing Ligand: Non-Apoptotic Signalling

Guerrache, Abderrahmane; Micheau, Olivier

http://dx.doi.org/10.3390/cells13060521

59 GLP1 Receptor Agonists-Effects beyond Obesity and Diabetes

Wilbon, Sydney S.; Kolonin, Mikhail G.

http://dx.doi.org/10.3390/cells13010065

60 The Role of Macrophages in the Pathogenesis of Atherosclerosis

Blagov, Alexander V.; Markin, Alexander M.; Bogatyreva, Anastasia I.; Tolstik, Taisiya V.; Sukhorukov, Vasily N.; Orekhov, Alexander N.

http://dx.doi.org/10.3390/cells12040522

61 Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Progress, Challenges, and Prospects

Tang, Shengjie; Qin, Chao; Hu, Haiyang; Liu, Tao; He, Yiwei; Guo, Haiyang; Yan, Hang; Zhang, Jun; Tang, Shoujun; Zhou, Haining

http://dx.doi.org/10.3390/cells11030320

62 Cross-Talk between NADPH Oxidase and Mitochondria: Role in ROS Signaling and Angiogenesis

Fukai, Tohru; Ushio-Fukai, Masuko

http://dx.doi.org/10.3390/cells9081849

63 Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes

Gurunathan, Sangiliyandi; Kang, Min-Hee; Jeyaraj, Muniyandi; Qasim, Muhammad; Kim, Jin-Hoi

http://dx.doi.org/10.3390/cells8040307

64 Cancer Vaccine Therapeutics: Limitations and Effectiveness-A Literature Review

Kaczmarek, Mariusz; Poznanska, Justyna; Fechner, Filip; Michalska, Natasza; Paszkowska, Sara; Napierala, Adrianna; Mackiewicz, Andrzej

http://dx.doi.org/10.3390/cells12172159

65 Microglia Mediated Neuroinflammation in Parkinsons Disease

Isik, Sevim; Kiyak, Bercem Yeman; Akbayir, Rumeysa; Seyhali, Rama; Arpaci, Tahire

http://dx.doi.org/10.3390/cells12071012

66 Therapeutic Targeting of NF-κB in Acute Lung Injury: A Double-Edged Sword

Millar, Michelle Warren; Fazal, Fabeha; Rahman, Arshad

http://dx.doi.org/10.3390/cells11203317

67 A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ

Lam, Jacob; Katti, Prasanna; Biete, Michelle; Mungai, Margaret; AshShareef, Salma; Neikirk, Kit; Lopez, Edgar Garza; Vue, Zer; Christensen, Trace A.; Beasley, Heather K.; Rodman, Taylor A.; Murray, Sandra A.; Salisbury, Jeffrey L.; Glancy, Brian; Shao, Jianqiang; Pereira, Renata O.; Abel, E. Dale; Hinton, Antentor, Jr.

http://dx.doi.org/10.3390/cells10092177

68 Mesenchymal Stem Cell-Derived Exosomes and Other Extracellular Vesicles as New Remedies in the Therapy of Inflammatory Diseases

Harrell, Carl Randall; Jovicic, Nemanja; Djonov, Valentin; Arsenijevic, Nebojsa; Volarevic, Vladislav

http://dx.doi.org/10.3390/cells8121605

69 Oxidative Stress and the NLRP3 Inflammasome: Focus on Female Fertility and Reproductive Health

Moustakli, Efthalia; Stavros, Sofoklis; Katopodis, Periklis; Skentou, Charikleia; Potiris, Anastasios; Panagopoulos, Periklis; Domali, Ekaterini; Arkoulis, Ioannis; Karampitsakos, Theodoros; Sarafi, Eleftheria; Michaelidis, Theologos M.; Zachariou, Athanasios; Zikopoulos, Athanasios

http://dx.doi.org/10.3390/cells14010036

70 NF-κB and JAK/STAT Signaling Pathways as Crucial Regulators of Neuroinflammation and Astrocyte Modulation in Spinal Cord Injury

Ageeva, Tatyana; Rizvanov, Albert; Mukhamedshina, Yana

http://dx.doi.org/10.3390/cells13070581

71 Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease

Ho, Hsin-Jung; Shirakawa, Hitoshi

http://dx.doi.org/10.3390/cells12010088

72 S100A8/A9 Is a Marker for the Release of Neutrophil Extracellular Traps and Induces Neutrophil Activation

Sprenkeler, Evelien G. G.; Zandstra, Judith; van Kleef, Nadine D.; Goetschalckx, Ines; Verstegen, Bibian; Aarts, Cathelijn E. M.; Janssen, Hans; Tool, Anton T. J.; van Mierlo, Gerard; van Bruggen, Robin; Jongerius, Ilse; Kuijpers, Taco W.

http://dx.doi.org/10.3390/cells11020236

73 Loop-Mediated Isothermal Amplification (LAMP): The Better Sibling of PCR?

Soroka, Marianna; Wasowicz, Barbara; Rymaszewska, Anna

http://dx.doi.org/10.3390/cells10081931

74 scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli Cells

Wang, Zhengpin; Xu, Xiaojiang

http://dx.doi.org/10.3390/cells9040920

75 Mesenchymal Stem Cell Migration and Tissue Repair

Fu, Xiaorong; Liu, Ge; Halim, Alexander; Ju, Yang; Luo, Qing; Song, Guanbin

http://dx.doi.org/10.3390/cells8080784

76 The CytoskeletonA Complex Interacting Meshwork

Hohmann, Tim; Dehghani, Faramarz

http://dx.doi.org/10.3390/cells8040362

77 Molecular Mechanisms in Autoimmune Thyroid Disease

Vargas-Uricoechea, Hernando

http://dx.doi.org/10.3390/cells12060918

78 Properties and Functions of Fibroblasts and Myofibroblasts in Myocardial Infarction

Venugopal, Harikrishnan; Hanna, Anis; Humeres, Claudio; Frangogiannis, Nikolaos G.

http://dx.doi.org/10.3390/cells11091386

79 Macrophage Reprogramming and Cancer Therapeutics: Role of iNOS-Derived NO

Kashfi, Khosrow; Kannikal, Jasmine; Nath, Niharika

http://dx.doi.org/10.3390/cells10113194

80 The RHO Family GTPases: Mechanisms of Regulation and Signaling

Mosaddeghzadeh, Niloufar; Ahmadian, Mohammad Reza

http://dx.doi.org/10.3390/cells10071831

81 Helicobacter pylori Virulence Factors-Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

Baj, Jacek; Forma, Alicja; Sitarz, Monika; Portincasa, Piero; Garruti, Gabriella; Krasowska, Danuta; Maciejewski, Ryszard

http://dx.doi.org/10.3390/cells10010027

82 The Intestinal Barrier and Current Techniques for the Assessment of Gut Permeability

Schoultz, Ida; Keita, Asa V.

http://dx.doi.org/10.3390/cells9081909

83 TGF-β in Hepatic Stellate Cell Activation and Liver Fibrogenesis-Updated 2019

Dewidar, Bedair; Meyer, Christoph; Dooley, Steven; Meindl-Beinker, Nadja

http://dx.doi.org/10.3390/cells8111419

84 Human Papilloma Virus-Associated Cervical Cancer and Health Disparities

Olusola, Patti; Banerjee, Hirendra Nath; Philley, Julie, V; Dasgupta, Santanu

http://dx.doi.org/10.3390/cells8060622

85 The MSC-EV-microRNAome: A Perspective on Therapeutic Mechanisms of Action in Sepsis and ARDS

dos Santos, Claudia C.; Lopes-Pacheco, Miqueias; English, Karen; Enes, Sara Rolandsson; Krasnodembskaya, Anna; Rocco, Patricia R. M.

http://dx.doi.org/10.3390/cells13020122

86 A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell-Cell Communication

Cheng, Changde; Chen, Wenan; Jin, Hongjian; Chen, Xiang

http://dx.doi.org/10.3390/cells12151970

87 Inflammation: A Target for Treatment in Spinal Cord Injury

Freyermuth-Trujillo, Ximena; Segura-Uribe, Julia J.; Salgado-Ceballos, Hermelinda; Orozco-Barrios, Carlos E.; Coyoy-Salgado, Angelica

http://dx.doi.org/10.3390/cells11172692

88 The Role of Mitochondria in Oocyte Maturation

Kirillova, Anastasia; Smitz, Johan E. J.; Sukhikh, Gennady T.; Mazunin, Ilya

http://dx.doi.org/10.3390/cells10092484

89 Inflammatory Cytokines in Cancer: Comprehensive Understanding and Clinical Progress in Gene Therapy

Lan, Tianxia; Chen, Li; Wei, Xiawei

http://dx.doi.org/10.3390/cells10010100

90 Metalloproteinases and Their Inhibitors: Potential for the Development of New Therapeutics

Raeeszadeh-Sarmazdeh, Maryam; Do, Linh D.; Hritz, Brianne G.

http://dx.doi.org/10.3390/cells9051313

91 The Non-Canonical Aspects of MicroRNAs: Many Roads to Gene Regulation

Stavast, Christiaan J.; Erkeland, Stefan J.

http://dx.doi.org/10.3390/cells8111465

92 The Role of Inflammation in Cancer: Mechanisms of Tumor Initiation, Progression, and Metastasis

Nishida, Atsushi; Andoh, Akira

http://dx.doi.org/10.3390/cells14070488

93 Recent Research Trends in Neuroinflammatory and Neurodegenerative Disorders

Cohen, Jessica; Mathew, Annette; Dourvetakis, Kirk D.; Sanchez-Guerrero, Estella; Pangeni, Rajendra P.; Gurusamy, Narasimman; Aenlle, Kristina K.; Ravindran, Geeta; Twahir, Assma; Isler, Dylan; Sosa-Garcia, Sara Rukmini; Llizo, Axel; Bested, Alison C.; Theoharides, Theoharis C.; Klimas, Nancy G.; Kempuraj, Duraisamy

http://dx.doi.org/10.3390/cells13060511

94 Update on Targeted Therapy and Immunotherapy for Metastatic Colorectal Cancer

Underwood, Patrick W.; Ruff, Samantha M.; Pawlik, Timothy M.

http://dx.doi.org/10.3390/cells13030245

95 Involvement of Astrocytes in the Formation, Maintenance, and Function of the Blood-Brain Barrier

Schiera, Gabriella; Di Liegro, Carlo Maria; Schiro, Giuseppe; Sorbello, Gabriele; Di Liegro, Italia

http://dx.doi.org/10.3390/cells13020150

96 Mitochondrial Impairment: A Common Motif in Neuropsychiatric Presentation? The Link to the Tryptophan-Kynurenine Metabolic System

Tanaka, Masaru; Szabo, Agnes; Spekker, Eleonora; Polyak, Helga; Toth, Fanni; Vecsei, Laszlo

http://dx.doi.org/10.3390/cells11162607

97 Sorting Mechanisms for MicroRNAs into Extracellular Vesicles and Their Associated Diseases

Groot, Michael; Lee, Heedoo

http://dx.doi.org/10.3390/cells9041044

98 Myeloid-Derived Suppressor Cells as a Therapeutic Target for Cancer

Law, Andrew M. K.; Valdes-Mora, Fatima; Gallego-Ortega, David

http://dx.doi.org/10.3390/cells9030561

99 Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

Park, Mi Hee; Hong, Jin Tae

http://dx.doi.org/10.3390/cells5020015

100 From Homeostasis to Neuroinflammation: Insights into Cellular and Molecular Interactions and Network Dynamics

Mueller, Ludmila; Di Benedetto, Svetlana; Mueller, Viktor

http://dx.doi.org/10.3390/cells14010054

101 Gut-Microbiota-Derived Metabolites Maintain Gut and Systemic Immune Homeostasis

Wang, Juanjuan; Zhu, Ningning; Su, Xiaomin; Gao, Yunhuan; Yang, Rongcun

http://dx.doi.org/10.3390/cells12050793

102 GBA Variants and Parkinson Disease: Mechanisms and Treatments

Smith, Laura; Schapira, Anthony H. V.

http://dx.doi.org/10.3390/cells11081261

103 Oxidative Stress in Human Pathology and Aging: Molecular Mechanisms and Perspectives

Hajam, Younis Ahmad; Rani, Raksha; Ganie, Shahid Yousuf; Sheikh, Tariq Ahmad; Javaid, Darakhshan; Qadri, Syed Sanober; Pramodh, Sreepoorna; Alsulimani, Ahmad; Alkhanani, Mustfa F.; Harakeh, Steve; Hussain, Arif; Haque, Shafiul; Reshi, Mohd Salim

http://dx.doi.org/10.3390/cells11030552

104 Reactive Oxygen Species and Redox Signaling in Chronic Kidney Disease

Irazabal, Maria, V; Torres, Vicente E.

http://dx.doi.org/10.3390/cells9061342

105 Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

Poitelon, Yannick; Kopec, Ashley M.; Belin, Sophie

http://dx.doi.org/10.3390/cells9040812

106 Oxidative Stress and Redox Imbalance: Common Mechanisms in Cancer Stem Cells and Neurodegenerative Diseases

Selvaraj, Nikhil Raj; Nandan, Durga; Nair, Bipin G.; Nair, Vipin A.; Venugopal, Parvathy; Aradhya, Rajaguru

http://dx.doi.org/10.3390/cells14070511

107 The Role of Inflammation in CKD

Kadatane, Saurav Prashant; Satariano, Matthew; Massey, Michael; Mongan, Kai; Raina, Rupesh

http://dx.doi.org/10.3390/cells12121581

108 Insights into the Interactions among Roots, Rhizosphere, and Rhizobacteria for Improving Plant Growth and Tolerance to Abiotic Stresses: A Review

Khan, Naeem; Ali, Shahid; Shahid, Muhammad Adnan; Mustafa, Adnan; Sayyed, R. Z.; Cura, Jose Alfredo

http://dx.doi.org/10.3390/cells10061551

109 Apoptosis: A Comprehensive Overview of Signaling Pathways, Morphological Changes, and Physiological Significance and Therapeutic Implications

Mustafa, Mohd; Ahmad, Rizwan; Tantry, Irfan Qadir; Ahmad, Waleem; Siddiqui, Sana; Alam, Mudassir; Abbas, Kashif; Hassan, Md. Imtaiyaz; Habib, Safia; Islam, Sidra

http://dx.doi.org/10.3390/cells13221838

110 The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds

Roy, Tithi; Boateng, Samuel T.; Uddin, Mohammad B.; Banang-Mbeumi, Sergette; Yadav, Rajesh K.; Bock, Chelsea R.; Folahan, Joy T.; Siwe-Noundou, Xavier; Walker, Anthony L.; King, Judy A.; Buerger, Claudia; Huang, Shile; Chamcheu, Jean Christopher

http://dx.doi.org/10.3390/cells12121671

111 Network Regulation of microRNA Biogenesis and Target Interaction

Komatsu, Shintaro; Kitai, Hiroki; Suzuki, Hiroshi I.

http://dx.doi.org/10.3390/cells12020306

112 From Molecular Mechanisms to Therapeutics: Understanding MicroRNA-21 in Cancer

Rhim, Jiho; Baek, Woosun; Seo, Yoona; Kim, Jong Heon

http://dx.doi.org/10.3390/cells11182791

113 Mesenchymal Stem Cell-Derived Secretome: A Potential Therapeutic Option for Autoimmune and Immune-Mediated Inflammatory Diseases

Muzes, Gyorgyi; Sipos, Ferenc

http://dx.doi.org/10.3390/cells11152300

114 Latest Developed Strategies to Minimize the Off-Target Effects in CRISPR-Cas-Mediated Genome Editing

Naeem, Muhammad; Majeed, Saman; Hoque, Mubasher Zahir; Ahmad, Irshad

http://dx.doi.org/10.3390/cells9071608

115 Cancer Stem Cell Functions in Hepatocellular Carcinoma and Comprehensive Therapeutic Strategies

Liu, Yu-Chin; Yeh, Chau-Ting; Lin, Kwang-Huei

http://dx.doi.org/10.3390/cells9061331

116 A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping

Romano, Maria; Ruggiero, Alessia; Squeglia, Flavia; Maga, Giovanni; Berisio, Rita

http://dx.doi.org/10.3390/cells9051267

117 Heat Shock Proteins: Agents of Cancer Development and Therapeutic Targets in Anti-Cancer Therapy

Yun, Chul Won; Kim, Hyung Joo; Lim, Ji Ho; Lee, Sang Hun

http://dx.doi.org/10.3390/cells9010060

118 Amyloid Beta and Phosphorylated Tau-Induced Defective Autophagy and Mitophagy in Alzheimers Disease

Reddy, P. Hemachandra; Oliver, Darryll M. A.

http://dx.doi.org/10.3390/cells8050488

119 Phosphorylations and Acetylations of Cytochrome c Control Mitochondrial Respiration, Mitochondrial Membrane Potential, Energy, ROS, and Apoptosis

Morse, Paul T.; Arroum, Tasnim; Wan, Junmei; Pham, Lucynda; Vaishnav, Asmita; Bell, Jamie; Pavelich, Lauren; Malek, Moh H.; Sanderson, Thomas H.; Edwards, Brian F. P.; Huttemann, Maik

http://dx.doi.org/10.3390/cells13060493

120 Aging of the Immune System: Focus on Natural Killer Cells Phenotype and Functions

Brauning, Ashley; Rae, Michael; Zhu, Gina; Fulton, Elena; Admasu, Tesfahun Dessale; Stolzing, Alexandra; Sharma, Amit

http://dx.doi.org/10.3390/cells11061017

121 Multifactorial Mechanism of Sarcopenia and Sarcopenic Obesity. Role of Physical Exercise, Microbiota and Myokines

Bilski, Jan; Pierzchalski, Piotr; Szczepanik, Marian; Bonior, Joanna; Zoladz, Jerzy A.

http://dx.doi.org/10.3390/cells11010160

122 Regulation of TNF-Induced Osteoclast Differentiation

Yao, Zhenqiang; Getting, Stephen J.; Locke, Ian C.

http://dx.doi.org/10.3390/cells11010132

123 Methods for Separation and Characterization of Extracellular Vesicles: Results of a Worldwide Survey Performed by the ISEV Rigor and Standardization Subcommittee

Royo, Felix; Thery, Clotilde; Falcon-Perez, Juan M.; Nieuwland, Rienk; Witwer, Kenneth W.

http://dx.doi.org/10.3390/cells9091955

124 Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles

Saint-Pol, Julien; Gosselet, Fabien; Duban-Deweer, Sophie; Pottiez, Gwenael; Karamanos, Yannis

http://dx.doi.org/10.3390/cells9040851

125 PC12 Cell Line: Cell Types, Coating of Culture Vessels, Differentiation and Other Culture Conditions

Wiatrak, Benita; Kubis-Kubiak, Adriana; Piwowar, Agnieszka; Barg, Ewa

http://dx.doi.org/10.3390/cells9040958

126 Current Strategies to Target Tumor-Associated-Macrophages to Improve Anti-Tumor Immune Responses

Anfray, Clement; Ummarino, Aldo; Torres Andon, Fernando; Allavena, Paola

http://dx.doi.org/10.3390/cells9010046

127 Mitochondrial Uncoupling: A Key Controller of Biological Processes in Physiology and Diseases

Demine, Stephane; Renard, Patricia; Arnould, Thierry

http://dx.doi.org/10.3390/cells8080795

128 Flow Cytometry: The Next Revolution

Robinson, J. Paul; Ostafe, Raluca; Iyengar, Sharath Narayana; Rajwa, Bartek; Fischer, Rainer

http://dx.doi.org/10.3390/cells12141875

129 Current Understanding of Asthma Pathogenesis and Biomarkers

Habib, Nazia; Pasha, Muhammad Asghar; Tang, Dale D.

http://dx.doi.org/10.3390/cells11172764

130 Innovative Treatment Strategies to Accelerate Wound Healing: Trajectory and Recent Advancements

Kolimi, Praveen; Narala, Sagar; Nyavanandi, Dinesh; Youssef, Ahmed Adel Ali; Dudhipala, Narendar

http://dx.doi.org/10.3390/cells11152439

131 Microglia Phenotypes in Aging and Neurodegenerative Diseases

Wendimu, Menbere Y.; Hooks, Shelley B.

http://dx.doi.org/10.3390/cells11132091

132 Molecular Mechanisms Responsible for Therapeutic Potential of Mesenchymal Stem Cell-Derived Secretome

Harrell, Carl Randall; Fellabaum, Crissy; Jovicic, Nemanja; Djonov, Valentin; Arsenijevic, Nebojsa; Volarevic, Vladislav

http://dx.doi.org/10.3390/cells8050467

133 Eosinophilic Asthma: Pathophysiology and Therapeutic Horizons

Hussain, Musaddique; Liu, Gang

http://dx.doi.org/10.3390/cells13050384

134 ICAMs in Immunity, Intercellular Adhesion and Communication

Guerra-Espinosa, Claudia; Jimenez-Fernandez, Maria; Sanchez-Madrid, Francisco; Serrador, Juan M.

http://dx.doi.org/10.3390/cells13040339

135 Interconnections between Inflammageing and Immunosenescence during Ageing

Teissier, Thibault; Boulanger, Eric; Cox, Lynne S.

http://dx.doi.org/10.3390/cells11030359

136 Emerging Role of cAMP/AMPK Signaling

Aslam, Muhammad; Ladilov, Yury

http://dx.doi.org/10.3390/cells11020308

137 Recent Advances in Understanding the Pathogenesis of Rheumatoid Arthritis: New Treatment Strategies

Mueller, Anna-Lena; Payandeh, Zahra; Mohammadkhani, Niloufar; Mubarak, Shaden M. H.; Zakeri, Alireza; Alagheband Bahrami, Armina; Brockmueller, Aranka; Shakibaei, Mehdi

http://dx.doi.org/10.3390/cells10113017

138 ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer

Sugiura, Reiko; Satoh, Ryosuke; Takasaki, Teruaki

http://dx.doi.org/10.3390/cells10102509

139 The Role of MSC in Wound Healing, Scarring and Regeneration

Guillamat-Prats, Raquel

http://dx.doi.org/10.3390/cells10071729

140 Metabolomics-Driven Biomarker Discovery for Breast Cancer Prognosis and Diagnosis

Kaur, Rasanpreet; Gupta, Saurabh; Kulshrestha, Sunanda; Khandelwal, Vishal; Pandey, Swadha; Kumar, Anil; Sharma, Gaurav; Kumar, Umesh; Parashar, Deepak; Das, Kaushik

http://dx.doi.org/10.3390/cells14010005

141 NF-κB as an Inducible Regulator of Inflammation in the Central Nervous System

Anilkumar, Sudha; Wright-Jin, Elizabeth

http://dx.doi.org/10.3390/cells13060485

142 Multifunctional Role of S100 Protein Family in the Immune System: An Update

Singh, Parul; Ali, Syed Azmal

http://dx.doi.org/10.3390/cells11152274

143 Exosome-Mediated Immunosuppression in Tumor Microenvironments

Xie, Qi-Hui; Zheng, Ji-Qi; Ding, Jia-Yi; Wu, Yu-Fei; Liu, Luisa; Yu, Zi-Li; Chen, Gang

http://dx.doi.org/10.3390/cells11121946

144 NAC Transcription Factor Family Regulation of Fruit Ripening and Quality: A Review

Liu, Gang-Shuai; Li, Hong-Li; Grierson, Donald; Fu, Da-Qi

http://dx.doi.org/10.3390/cells11030525

145 The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization

Turathum, Bongkoch; Gao, Er-Meng; Chian, Ri-Cheng

http://dx.doi.org/10.3390/cells10092292

146 Role of Structural and Non-Structural Proteins and Therapeutic Targets of SARS-CoV-2 for COVID-19

Yadav, Rohitash; Chaudhary, Jitendra Kumar; Jain, Neeraj; Chaudhary, Pankaj Kumar; Khanra, Supriya; Dhamija, Puneet; Sharma, Ambika; Kumar, Ashish; Handu, Shailendra

http://dx.doi.org/10.3390/cells10040821

147 Ferroptosis and Cancer: Mitochondria Meet the Iron Maiden Cell Death

Battaglia, Anna Martina; Chirillo, Roberta; Aversa, Ilenia; Sacco, Alessandro; Costanzo, Francesco; Biamonte, Flavia

http://dx.doi.org/10.3390/cells9061505

148 Oligodendrocytes in Development, Myelin Generation and Beyond

Kuhn, Sarah; Gritti, Laura; Crooks, Daniel; Dombrowski, Yvonne

http://dx.doi.org/10.3390/cells8111424

149 Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications

Doss, Michael Xavier; Sachinidis, Agapios

http://dx.doi.org/10.3390/cells8050403

150 Molecular Mechanisms of Inflammation in Sarcopenia: Diagnosis and Therapeutic Update

Elizabeth Jimenez-Gutierrez, Guadalupe; Edith Martinez-Gomez, Laura; Martinez-Armenta, Carlos; Pineda, Carlos; Angelica Martinez-Nava, Gabriela; Lopez-Reyes, Alberto

http://dx.doi.org/10.3390/cells11152359

151 Management of Rheumatoid Arthritis: An Overview

Radu, Andrei-Flavius; Bungau, Simona Gabriela

http://dx.doi.org/10.3390/cells10112857

152 Epithelial-Mesenchymal Transition (EMT): The Type-2 EMT in Wound Healing, Tissue Regeneration and Organ Fibrosis

Marconi, Guya D.; Fonticoli, Luigia; Rajan, Thangavelu Soundara; Pierdomenico, Sante D.; Trubiani, Oriana; Pizzicannella, Jacopo; Diomede, Francesca

http://dx.doi.org/10.3390/cells10071587

153 Osteoblast-Osteoclast Communication and Bone Homeostasis

Kim, Jung-Min; Lin, Chujiao; Stavre, Zheni; Greenblatt, Matthew B.; Shim, Jae-Hyuck

http://dx.doi.org/10.3390/cells9092073

154 Hyaluronic Acid: Redefining Its Role

Abatangelo, G.; Vindigni, V.; Avruscio, G.; Pandis, L.; Brun, P.

http://dx.doi.org/10.3390/cells9071743

155 Astrocytes Maintain Glutamate Homeostasis in the CNS by Controlling the Balance between Glutamate Uptake and Release

Mahmoud, Shaimaa; Gharagozloo, Marjan; Simard, Camille; Gris, Denis

http://dx.doi.org/10.3390/cells8020184

156 A Brief Review of Bone Cell Function and Importance

Sromova, Veronika; Sobola, Dinara; Kaspar, Pavel

http://dx.doi.org/10.3390/cells12212576

157 Polyunsaturated Fatty Acids Drive Lipid Peroxidation during Ferroptosis

Mortensen, Michael S. S.; Ruiz, Jimena; Watts, Jennifer L. L.

http://dx.doi.org/10.3390/cells12050804

158 Diabetic Macular Edema: Current Understanding, Molecular Mechanisms and Therapeutic Implications

Zhang, Jingfa; Zhang, Jingxiang; Zhang, Chaoyang; Zhang, Jingting; Gu, Limin; Luo, Dawei; Qiu, Qinghua

http://dx.doi.org/10.3390/cells11213362

159 COVID-19: Characteristics and Therapeutics

Chilamakuri, Rameswari; Agarwal, Saurabh

http://dx.doi.org/10.3390/cells10020206

160 Influence of Nitrogen and Phosphorus on Microalgal Growth, Biomass, Lipid, and Fatty Acid Production: An Overview

Yaakob, Maizatul Azrina; Mohamed, Radin Maya Saphira Radin; Al-Gheethi, Adel; Aswathnarayana Gokare, Ravishankar; Ambati, Ranga Rao

http://dx.doi.org/10.3390/cells10020393

161 Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy

Yoshida, Tadashi; Delafontaine, Patrice

http://dx.doi.org/10.3390/cells9091970

162 Telomere Biology and Human Phenotype

Turner, Kara J.; Vasu, Vimal; Griffin, Darren K.

http://dx.doi.org/10.3390/cells8010073

163 Pathogenic Role of Immune Cells in Rheumatoid Arthritis: Implications in Clinical Treatment and Biomarker Development

Yap, Hooi-Yeen; Tee, Sabrina Zi-Yi; Wong, Magdelyn Mei-Theng; Chow, Sook-Khuan; Peh, Suat-Cheng; Teow, Sin-Yeang

http://dx.doi.org/10.3390/cells7100161

164 Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

Wood, Stephen J.; Kuzel, Timothy M.; Shafikhani, Sasha H.

http://dx.doi.org/10.3390/cells12010199

165 Macrophage-Mediated Inflammation in Skin Wound Healing

Hassanshahi, Alireza; Moradzad, Mohammad; Ghalamkari, Saman; Fadaei, Moosa; Cowin, Allison J.; Hassanshahi, Mohammadhossein

http://dx.doi.org/10.3390/cells11192953

166 Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy

Degirmenci, Ufuk; Wang, Mei; Hu, Jiancheng

http://dx.doi.org/10.3390/cells9010198

167 Cellular Stress Responses in Radiotherapy

Kim, Wanyeon; Lee, Sungmin; Seo, Danbi; Kim, Dain; Kim, Kyeongmin; Kim, EunGi; Kang, JiHoon; Seong, Ki Moon; Youn, HyeSook; Youn, BuHyun

http://dx.doi.org/10.3390/cells8091105

168 Mesenchymal Stem Cells for Regenerative Medicine

Han, Yu; Li, Xuezhou; Zhang, Yanbo; Han, Yuping; Chang, Fei; Ding, Jianxun

http://dx.doi.org/10.3390/cells8080886

169 The Role of Oxidative Stress in Tumorigenesis and Progression

Li, Kexin; Deng, Zhangyuzi; Lei, Chunran; Ding, Xiaoqing; Li, Jing; Wang, Changshan

http://dx.doi.org/10.3390/cells13050441

170 Targeting the Ubiquitin-Proteasome System and Recent Advances in Cancer Therapy

Spano, Daniela; Catara, Giuliana

http://dx.doi.org/10.3390/cells13010029

171 Mechanisms of Blood-Brain Barrier Protection by Microbiota-Derived Short-Chain Fatty Acids

Fock, Ekaterina; Parnova, Rimma

http://dx.doi.org/10.3390/cells12040657

172 Mitophagy: Molecular Mechanisms, New Concepts on Parkin Activation and the Emerging Role of AMPK/ULK1 Axis

Iorio, Roberto; Celenza, Giuseppe; Petricca, Sabrina

http://dx.doi.org/10.3390/cells11010030

173 Chronic Diabetic Wounds and Their Treatment with Skin Substitutes

Holl, Jordan; Kowalewski, Cezary; Zimek, Zbigniew; Fiedor, Piotr; Kaminski, Artur; Oldak, Tomasz; Moniuszko, Marcin; Eljaszewicz, Andrzej

http://dx.doi.org/10.3390/cells10030655

174 Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19

Tomar, Bhawna; Anders, Hans-Joachim; Desai, Jyaysi; Mulay, Shrikant R.

http://dx.doi.org/10.3390/cells9061383

175 Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives

Roehlen, Natascha; Crouchet, Emilie; Baumert, Thomas F.

http://dx.doi.org/10.3390/cells9040875

176 Regeneration or Repair? The Role of Alveolar Epithelial Cells in the Pathogenesis of Idiopathic Pulmonary Fibrosis (IPF)

Confalonieri, Paola; Volpe, Maria Concetta; Jacob, Justin; Maiocchi, Serena; Salton, Francesco; Ruaro, Barbara; Confalonieri, Marco; Braga, Luca

http://dx.doi.org/10.3390/cells11132095

177 Inflammation in Parkinsons Disease: Mechanisms and Therapeutic Implications

Pajares, Marta; Rojo, Ana, I; Manda, Gina; Bosca, Lisardo; Cuadrado, Antonio

http://dx.doi.org/10.3390/cells9071687

178 The Osteosarcoma Microenvironment: A Complex but Targetable Ecosystem

Corre, Isabelle; Verrecchia, Franck; Crenn, Vincent; Redini, Francoise; Trichet, Valerie

http://dx.doi.org/10.3390/cells9040976

179 Mesenchymal Stem Cell Derived Extracellular Vesicles for Tissue Engineering and Regenerative Medicine Applications

Tsiapalis, Dimitrios; ODriscoll, Lorraine

http://dx.doi.org/10.3390/cells9040991

180 Role of JAK/STAT3 Signaling in the Regulation of Metastasis, the Transition of Cancer Stem Cells, and Chemoresistance of Cancer by Epithelial-Mesenchymal Transition

Jin, Wook

http://dx.doi.org/10.3390/cells9010217

181 Role of Cardiolipin in Mitochondrial Function and Dynamics in Health and Disease: Molecular and Pharmacological Aspects

Paradies, Giuseppe; Paradies, Valeria; Ruggiero, Francesca M.; Petrosillo, Giuseppe

http://dx.doi.org/10.3390/cells8070728

182 Molecular Mechanisms of Alzheimers Disease Induced by Amyloid-β and Tau Phosphorylation Along with RhoA Activity: Perspective of RhoA/Rho-Associated Protein Kinase Inhibitors for Neuronal Therapy

Ahn, Eun Hee; Park, Jae-Bong

http://dx.doi.org/10.3390/cells14020089

183 Implementing Whole Genome Sequencing (WGS) in Clinical Practice: Advantages, Challenges, and Future Perspectives

Brlek, Petar; Bulic, Luka; Bracic, Matea; Projic, Petar; Skaro, Vedrana; Shah, Nidhi; Shah, Parth; Primorac, Dragan

http://dx.doi.org/10.3390/cells13060504

184 Interaction of Mitochondrial Calcium and ROS in Neurodegeneration

Baev, Artyom Y.; Vinokurov, Andrey Y.; Novikova, Irina N.; Dremin, Viktor V.; Potapova, Elena V.; Abramov, Andrey Y.

http://dx.doi.org/10.3390/cells11040706

185 Spheroid Culture System Methods and Applications for Mesenchymal Stem Cells

Ryu, Na-Eun; Lee, Soo-Hong; Park, Hansoo

http://dx.doi.org/10.3390/cells8121620

186 The Regulation of NF-κB Subunits by Phosphorylation

Christian, Frank; Smith, Emma L.; Carmody, Ruaidhri J.

http://dx.doi.org/10.3390/cells5010012

187 Allogeneic CAR-T Therapy Technologies: Has the Promise Been Met?

Lonez, Caroline; Breman, Eytan

http://dx.doi.org/10.3390/cells13020146

188 GFAP as a Potential Biomarker for Alzheimers Disease: A Systematic Review and Meta-Analysis

Kim, Ka Young; Shin, Ki Young; Chang, Keun-A

http://dx.doi.org/10.3390/cells12091309

189 Doxorubicin-An Agent with Multiple Mechanisms of Anticancer Activity

Kciuk, Mateusz; Gielecinska, Adrianna; Mujwar, Somdutt; Kolat, Damian; Kaluzinska-Kolat, Zaneta; Celik, Ismail; Kontek, Renata

http://dx.doi.org/10.3390/cells12040659

190 The Role of Gut Dysbiosis in the Pathophysiology of Neuropsychiatric Disorders

Anand, Nikhilesh; Gorantla, Vasavi Rakesh; Chidambaram, Saravana Babu

http://dx.doi.org/10.3390/cells12010054

191 Molecular Mechanisms of Ferroptosis and Relevance to Cardiovascular Disease

Xie, Lai-Hua; Fefelova, Nadezhda; Pamarthi, Sri Harika; Gwathmey, Judith K.

http://dx.doi.org/10.3390/cells11172726

192 The Influence of Gut Dysbiosis in the Pathogenesis and Management of Ischemic Stroke

Chidambaram, Saravana Babu; Rathipriya, Annan Gopinath; Mahalakshmi, Arehally M.; Sharma, Sonali; Hediyal, Tousif Ahmed; Ray, Bipul; Sunanda, Tuladhar; Rungratanawanich, Wiramon; Kashyap, Rajpal Singh; Qoronfleh, M. Walid; Essa, Musthafa Mohamed; Song, Byoung-Joon; Monaghan, Tanya M.

http://dx.doi.org/10.3390/cells11071239

193 High-Fat, Western-Style Diet, Systemic Inflammation, and Gut Microbiota: A Narrative Review

Malesza, Ida Judyta; Malesza, Michal; Walkowiak, Jaroslaw; Mussin, Nadiar; Walkowiak, Dariusz; Aringazina, Raisa; Bartkowiak-Wieczorek, Joanna; Madry, Edyta

http://dx.doi.org/10.3390/cells10113164

194 GSK-3 and Tau: A Key Duet in Alzheimers Disease

Sayas, Carmen Laura; Avila, Jesus

http://dx.doi.org/10.3390/cells10040721

195 Role of Cardiac Macrophages on Cardiac Inflammation, Fibrosis and Tissue Repair

Lafuse, William P.; Wozniak, Daniel J.; Rajaram, Murugesan V. S.

http://dx.doi.org/10.3390/cells10010051

196 Update on the Pathomechanism, Diagnosis, and Treatment Options for Rheumatoid Arthritis

Lin, Yen-Ju; Anzaghe, Martina; Schuelke, Stefan

http://dx.doi.org/10.3390/cells9040880

197 Therapeutic Targets in Glioblastoma: Molecular Pathways, Emerging Strategies, and Future Directions

Tang, Justin; Karbhari, Nishika; Campian, Jian L.

http://dx.doi.org/10.3390/cells14070494

198 Ubiquitination-Proteasome System (UPS) and Autophagy Two Main Protein Degradation Machineries in Response to Cell Stress

Li, Yanan; Li, Shujing; Wu, Huijian

http://dx.doi.org/10.3390/cells11050851

199 Fibronectin: Molecular Structure, Fibrillar Structure and Mechanochemical Signaling

Dalton, Caleb J.; Lemmon, Christopher A.

http://dx.doi.org/10.3390/cells10092443

200 Effects of Salinity Stress on Chloroplast Structure and Function

Hameed, Abdul; Ahmed, Muhammad Zaheer; Hussain, Tabassum; Aziz, Irfan; Ahmad, Niaz; Gul, Bilquees; Nielsen, Brent L.

http://dx.doi.org/10.3390/cells10082023

201 Signaling Pathways in Cancer: Therapeutic Targets, Combinatorial Treatments, and New Developments

Yip, Hon Yan Kelvin; Papa, Antonella

http://dx.doi.org/10.3390/cells10030659

202 NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction

Choi, Moon-Chang; Jo, Jiwon; Park, Jonggwan; Kang, Hee Kyoung; Park, Yoonkyung

http://dx.doi.org/10.3390/cells8070734

203 Autophagy: An Essential Degradation Program for Cellular Homeostasis and Life

Chun, Yoomi; Kim, Joungmok

http://dx.doi.org/10.3390/cells7120278

204 The Role of Cortisol in Chronic Stress, Neurodegenerative Diseases, and Psychological Disorders

Knezevic, Emilija; Nenic, Katarina; Milanovic, Vladislav; Knezevic, Nebojsa Nick

http://dx.doi.org/10.3390/cells12232726

205 The Role of the Immune System in the Development of Endometriosis

Abramiuk, Monika; Grywalska, Ewelina; Malkowska, Paulina; Sierawska, Olga; Hrynkiewicz, Rafal; Niedzwiedzka-Rystwej, Paulina

http://dx.doi.org/10.3390/cells11132028

206 The Good and the Bad: Monocytes and Macrophages Diverse Functions in Inflammation

Austermann, Judith; Roth, Johannes; Barczyk-Kahlert, Katarzyna

http://dx.doi.org/10.3390/cells11121979

207 Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine

Hade, Mangesh D.; Suire, Caitlin N.; Suo, Zucai

http://dx.doi.org/10.3390/cells10081959

208 Calcium Signaling Regulates Autophagy and Apoptosis

Sukumaran, Pramod; Da Conceicao, Viviane Nascimento; Sun, Yuyang; Ahamad, Naseem; Saraiva, Luis R.; Selvaraj, Senthil; Singh, Brij B.

http://dx.doi.org/10.3390/cells10082125

209 Immune Infiltrates in Breast Cancer: Recent Updates and Clinical Implications

Dieci, Maria Vittoria; Miglietta, Federica; Guarneri, Valentina

http://dx.doi.org/10.3390/cells10020223

210 Vitamin B6 and Its Role in Cell Metabolism and Physiology

Parra, Marcelina; Stahl, Seth; Hellmann, Hanjo

http://dx.doi.org/10.3390/cells7070084

211 Emerging Immunotherapy Approaches for Advanced Clear Cell Renal Cell Carcinoma

Meng, Lingbin; Collier, Katharine A.; Wang, Peng; Li, Zihai; Monk, Paul; Mortazavi, Amir; Hu, Zhiwei; Spakowicz, Daniel; Zheng, Linghua; Yang, Yuanquan

http://dx.doi.org/10.3390/cells13010034

212 The Role of TNF-α in Alzheimers Disease: A Narrative Review

Plantone, Domenico; Pardini, Matteo; Righi, Delia; Manco, Carlo; Colombo, Barbara Maria; De Stefano, Nicola

http://dx.doi.org/10.3390/cells13010054

213 The Role of HO-1 and Its Crosstalk with Oxidative Stress in Cancer Cell Survival

Chiang, Shih-Kai; Chen, Shuen-Ei; Chang, Ling-Chu

http://dx.doi.org/10.3390/cells10092401

214 The Ins and Outs of Cathepsins: Physiological Function and Role in Disease Management

Yadati, Tulasi; Houben, Tom; Bitorina, Albert; Shiri-Sverdlov, Ronit

http://dx.doi.org/10.3390/cells9071679

215 RNA-Based Therapeutics: From Antisense Oligonucleotides to miRNAs

Bajan, Sarah; Hutvagner, Gyorgy

http://dx.doi.org/10.3390/cells9010137

216 Mechanisms of Chemotherapy Resistance in Triple-Negative Breast Cancer-How We Can Rise to the Challenge

Nedeljkovic, Milica; Damjanovic, Ana

http://dx.doi.org/10.3390/cells8090957

2025年10月ESI热点论文

1 The Role of Inflammation in Cancer: Mechanisms of Tumor Initiation, Progression, and Metastasis

Nishida, Atsushi; Andoh, Akira

http://dx.doi.org/10.3390/cells14070488

2 Apoptosis: A Comprehensive Overview of Signaling Pathways, Morphological Changes, and Physiological Significance and Therapeutic Implications

Mustafa, Mohd; Ahmad, Rizwan; Tantry, Irfan Qadir; Ahmad, Waleem; Siddiqui, Sana; Alam, Mudassir; Abbas, Kashif; Hassan, Md. Imtaiyaz; Habib, Safia; Islam, Sidra

http://dx.doi.org/10.3390/cells13221838

3 Oxidative Stress and Redox Imbalance: Common Mechanisms in Cancer Stem Cells and Neurodegenerative Diseases

Selvaraj, Nikhil Raj; Nandan, Durga; Nair, Bipin G.; Nair, Vipin A.; Venugopal, Parvathy; Aradhya, Rajaguru

http://dx.doi.org/10.3390/cells14070511

4 Therapeutic Targets in Glioblastoma: Molecular Pathways, Emerging Strategies, and Future Directions

Tang, Justin; Karbhari, Nishika; Campian, Jian L.

http://dx.doi.org/10.3390/cells14070494