近日，重庆大学李必进团队研究了铱催化双重C-H活化和环化：获得抗卡沙发射和光敏磷光材料。该项研究成果发表在2025年10月20日出版的《美国化学会志》上。

首例兼具反卡沙发射特性、光敏性与磷光多功能材料，研究组已通过高效的双重C-H键活化环化策略成功合成。实验数据与理论计算共同证实了吩噻嗪鎓盐和吩噁嗪鎓盐的反卡沙发射特性。其中，吩噁嗪鎓盐凭借该特性可实现双通道发射强度比率成像，用于细胞及细胞间结构的可视化观测，同时具备特异性靶向活细胞线粒体的能力。

此外，这类新型光敏-磷光材料在C-H键官能团化反应中展现出高效光催化活性。值得注意的是，新型吩噻嗪鎓盐在聚乙烯醇薄膜中呈现光致变色与磷光双重特性：在光照下发生显著蓝移并伴随超长室温磷光，使其在加密存储与多通道信息存储领域具有重要应用前景。

附：英文原文

Title: Iridium-Catalyzed Twofold C–H/C–H Activation and Annulation: Access to Anti-Kasha Emission and Photosensitive-Phosphorescent Materials

Author: Tao Sun, Jingxian Zhang, Ju Zhang, Xianhui Yang, Danni Yang, Tingting Yang, Bijin Li

Issue&Volume: October 20, 2025

Abstract: The first example of a multifunctional anti-Kasha emission-photosensitive-phosphorescent material has been synthesized via an efficient twofold C–H/C–H activation and annulation protocol. Both experimental data and theoretical calculations have validated the anti-Kasha emission property of phenothiazinium and phenoxazinium salts. Specifically, the anti-Kasha emission property of phenoxazinium salts enables dual-channel emission intensity ratio imaging for visualizing cellular and intercellular structures, while also endowing them with the capability to specifically target mitochondria in living cells. Furthermore, these newly developed photosensitive-phosphorescent materials have been demonstrated to act as efficient photocatalysts in C–H bond functionalization reactions. In addition, the novel phenothiazinium salts demonstrate photosensitive and phosphorescent properties in PVA (poly(vinyl alcohol)) films: upon light irradiation, they undergo a significant blue shift accompanied by ultralong room-temperature phosphorescence, making them highly promising for applications in encryption and multichannel information storage.

DOI: 10.1021/jacs.5c14577

Source: https://pubs.acs.org/doi/abs/10.1021/jacs.5c14577