上海交通大学李涛团队报道了可见光激活杂芳基偶氮开关——迈向更加丰富多彩的未来。相关研究成果于2024年7月11日发表在国际知名学术期刊《美国化学会杂志》。

偶氮苯类化合物（Ph-N═N-Ph）被认为是研究最广泛的分子光开关，最近偶氮杂芳烃（Het-N \9552》N-Ph或Het-N’N-Het）的兴起为推进这一已经成熟的领域提供了巨大的机会。一个常见的限制是偶氮开关通常需要有害的紫外线才能激活，这阻碍了它们在各个领域的应用。尽管过去几十年来在开发可见光偶氮苯方面做出了巨大努力，但可见光杂芳基偶氮开关的潜力在很大程度上仍未得到探索。

该文总结了可见光杂芳基偶氮开关的最新进展，涵盖了分子设计策略、结构-性质关系和潜在应用。该文强调了偶氮杂芳烃在可见光开关的研究和开发中相对于偶氮苯的独特优势。此外，研究人员还讨论了这一新兴领域的机遇和挑战，并提出了解决光谱红移和热半衰期等关键问题的潜在解决方案。通过这篇透视论文，旨在为该领域的进一步探索提供灵感，以期可见光偶氮杂芳烃光开关的日益繁荣和光明的未来。

附：英文原文

Title: Visible-Light-Activated Heteroaryl Azoswitches: Toward a More Colorful Future

Author: Tongtong Dang, Zhao-Yang Zhang, Tao Li

Issue&Volume: July 11, 2024

Abstract: Azobenzenes (Ph-N═N-Ph) are known as the most widely studied molecular photoswitches, and the recent rise of azoheteroarenes (Het-N═N-Ph or Het-N═N-Het) offers great opportunities to advance this already mature field. A common limitation is that azo-switches generally require harmful UV light for activation, which hinders their application across various fields. Despite great efforts in developing visible-light azobenzenes over the past few decades, the potential of visible-light heteroaryl azoswitches remains largely unexplored. This Perspective summarizes the state-of-the-art advancements in visible-light heteroaryl azoswitches, covering molecular design strategies, the structure–property relationship, and potential applications. We highlight the distinctive advantages of azoheteroarenes over azobenzenes in the research and development of visible-light switches. Furthermore, we discuss the opportunities and challenges in this emerging field and propose potential solutions to address crucial issues such as spectral red-shift and thermal half-life. Through this Perspective paper, we aim to provide inspiration for further exploration in this field, in anticipation of the growing prosperity and bright future of visible-light azoheteroarene photoswitches.

DOI: 10.1021/jacs.4c03135

Source: https://pubs.acs.org/doi/abs/10.1021/jacs.4c03135