武汉大学雷爱文团队报道了Cu催化的C-H键转化的程序化交流优化。相关研究成果发表在2024年7月12日出版的国际学术期刊《科学》。

直流电合成在过去的一个世纪里经历了优化，在各种工业过程中起着关键作用。以极性反转和周期性波动为特征的交流电（AC）电合成可能有利于多种化学反应，但设备、原理和应用场景仍然不发达。

该文中，研究人员介绍了一种用于程序化交流（pAC）电合成的协议，该协议系统地调整电流、频率和占空比。代表性pAC波形的应用促进了铜催化的交叉偶联和双官能化反应中的碳氢键断裂，这些反应在直流和化学氧化条件下表现出次优性能。此外，观察不同波形应用下的催化剂动态变化提供了机理见解。

附：英文原文

Title: Programmed alternating current optimization of Cu-catalyzed C-H bond transformations

Author: Li Zeng, Qinghong Yang, Jianxing Wang, Xin Wang, Pengjie Wang, Shengchun Wang, Shide Lv, Shabbir Muhammad, Yichang Liu, Hong Yi, Aiwen Lei

Issue&Volume: 2024-07-12

Abstract: Direct current (DC) electrosynthesis, which has undergone optimization over the past century, plays a pivotal role in a variety of industrial processes. Alternating current (AC) electrosynthesis, characterized by polarity reversal and periodic fluctuations, may be advantageous for multiple chemical reactions, but apparatus, principles, and application scenarios remain underdeveloped. In this work, we introduce a protocol for programmed AC (pAC) electrosynthesis that systematically adjusts currents, frequencies, and duty ratios. The application of representative pAC waveforms facilitates copper-catalyzed carbon-hydrogen bond cleavage in cross-coupling and difunctionalization reactions that exhibit suboptimal performance under DC and chemical oxidation conditions. Moreover, observing catalyst dynamic variation under diverse waveform applications provides mechanistic insight.

DOI: ado0875

Source: https://www.science.org/doi/10.1126/science.ado0875