华中科技大学池小东团队开发出用于极性化合物分离的无孔自适应杯[4]吡咯晶体。相关研究成果于2021年11月8日发表在国际知名学术期刊《美国化学会杂志》。

使用分子晶体材料分离和纯化化学原料，特别是具有类似物理和化学性质的极性化合物，是一项持续的挑战。对于形成二元共沸物的挥发性原料尤其如此。

该文中，研究人员报告了一种新的杯[4]吡咯（C4P）腔扩展变体，该变体易于形成无孔自适应晶体（NACs）。该基于C4P的NACs能够从纯度接近100%的甲苯/吡啶混合物中分离吡啶，以及从具有高吸附能力的1,4-二氧六环/水混合物中去除1,4-二氧六环。通过在真空下加热从载客体的NACs中去除极性壳体（吡啶或1,4-二氧六环）产生无壳体结晶形式。对于这两种壳体，C4P材料可以重复使用，如10次吸收和释放循环所示，而不会出现明显的性能下降。

附：英文原文

Title: Nonporous Adaptive Calix[4]pyrrole Crystals for Polar Compound Separations

Author: Dan Luo, Jinya Tian, Jonathan L. Sessler, Xiaodong Chi

Issue&Volume: November 8, 2021

Abstract: The use of molecular crystalline materials for the separation and purification of chemical raw materials, particularly polar compounds with similar physical and chemical properties, represents an ongoing challenge. This is particularly true for volatile feedstocks that form binary azeotropes. Here we report a new cavity-extended version of calix[4]pyrrole (C4P) that readily forms nonporous adaptive crystals (NACs). These C4P-based NACs allow pyridine to be separated from toluene/pyridine mixtures with nearly 100% purity, as well as the removal of 1,4-dioxane from 1,4-dioxane/water mixtures with high adsorption capacity. Removal of the polar guest (pyridine or 1,4-dioxane) from the guest-loaded NACs by heating under vacuum produces the guest-free crystalline form. In the case of both guests, the C4P material could be reused as demonstrated through 10 uptake and release cycles without apparent performance loss.

DOI: 10.1021/jacs.1c09385

Source: https://pubs.acs.org/doi/10.1021/jacs.1c09385