直播时间：2026年5 月15日（周五）20:00-21:30

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直播简介

iCANX Talks 第269期将于5月15日北京时间晚8点正式开播，本期特邀肯特大学教授Adrian Podoleanu演讲，美国罗切斯特大学教授Susana Marcos，奥克兰大学教授Frederique Vanholsbeeck，萨里大学教授David Sampson，邓迪大学教授Chunhui Li作为研讨嘉宾，北京航空航天大学教授Xia Yu主持本场对话。顶尖学者云集，前沿科技碰撞，精彩即将呈现！

嘉宾介绍

Adrian Podoleanu

肯特大学

En-face optical coherence tomographybetween analog and digital signal processing

ABSTRACT

While microscopy evolved as an en-face technology, 1st optical coherence tomography (OCT) image was a cross section and in its 35 years of existence, OCT progressed mainly as a cross sectioning modality. The 1st OCT image we obtained in Kent was en-face and we continued to progress the OCT technology towards this less used orientation of image sections. Using modern OCT technology, based on spectral processing, delivery of an en-face section is conditioned by the process of delivering a 3D volume of a sample. This takes time and therefore, it was not until recent progress in fast OCT acquisition that restored the interest in en-face sectioning. In addition, to facilitate the en-face presentation, we introduced a novel signal processing modality, Leader Follower (LF) that disconnects the production of an en-face slice from the need to collect all the 3D data. LF-OCT can deliver one or more en-face OCT images from several depths with no need to assemble the whole volume of data. As acquisition speed is essential for en-face OCT views, we paid attention to ultra fast tunable lasers. By engaging the latest results in fast tunable laser technology, the OCT data acquisition is done quick. However, due to the large amount of data, conventional OCT signal processing based on many GS/s digitisers engaged in delivering cross sections and volumes lag behind and processing can only be completed in post acquisition. In other words, there is a bottleneck in terms of delivery of images in real time. I will show how a version of LF, downconversion LF-OCT, can be employed to deliver real time en-face views by recurring to analog downconversion. I will also show that DLF using analog multiplication is ideally suited for novel bidirectional tuning lasers to not only acquire the data quick, but deliver en-face images in real time with no need of stitching images created with the two sweeping directions.

尽管显微技术最初是作为正面成像技术发展起来的，但第一张光学相干断层扫描（OCT）图像仅呈现横截面视图；在其35年的发展历程中，OCT技术主要沿着横截面成像这一方向不断进步。我们在肯特地区获取的第一张OCT图像正是正面成像，此后我们持续推动OCT技术向这种较少使用的图像切片方向发展。基于光谱处理的现代OCT技术中，正面切片的生成取决于样本三维体积数据的采集过程——这一过程耗时较长，因此直到近期快速OCT采集技术取得突破后，正面切片技术才重新受到关注。此外，为优化正面成像效果，我们引入了一种新型信号处理模式“领头跟随器”（LF），该模式将正面切片的生成与完整三维数据采集解耦。LF-OCT可在无需整合全部数据的情况下，从多个深度获取一张或多张正面OCT图像。由于实时获取正面OCT视图对采集速度至关重要，我们重点采用了超快可调谐激光技术。通过应用最新的可调谐激光技术成果，OCT数据采集得以实现高速完成。然而，由于数据量庞大，传统基于多GS/s数字化仪的OCT信号处理在生成横截面和三维图像方面存在瓶颈，相关处理只能在采集完成后进行。换言之，实时图像传输仍面临技术瓶颈。我将演示如何利用LF的一种变体——下变频LF-OCT技术，通过采用模拟下变频方法实现实时正面视图的获取。同时还将证明：采用模拟乘法的 DLF 技术特别适用于新型双向调谐激光器，不仅能快速采集数据，还能实时生成正面图像，而无需对两个扫描方向生成的图像进行拼接处理。

BIOGRAPHY

Adrian Podoleanu (Fellow of the Royal Academy of Engineering, of the Institute of Physics, of Optica, of SPIE and an International Fellow of Chinese Optical Society) is the Head of the Applied Optics Group, Professor of Biomedical Optics in the Department of Engineering, Mathematics and Physics, University of Kent, Canterbury, UK, an investigator of the Biomedical Research Centre, University College London (UCL) and Institute of Ophthalmology, UK, and honorary professor in the UCL and in the University of Medicine and Pharmacy, Timisoara, Romania. He received the Ph.D. degree in Electronics from the Electronics and Telecommunications Faculty, Technical University of Bucharest, Romania, in 1984. He was a founder member of the Romanian Chapter of SPIE and its first Chairman (1992). While in Kent, he has obtained the first en-face optical coherence tomography (OCT) images from the retina in the human eye and reported the first combined OCT/scanning laser ophthalmoscopy instrument. According to Scholar GPS he is a highly ranked scholar – life time all, with a star for OCT and Tomography. Currently he serves as the Associate Secretary of the International Commission for Optics. AWARDS: Order of the Crown, officer, Royal House of Romania, 2017; Royal Society Wolfson Research Merit Award 2015; European Research Council, Advanced Research Fellowship, 2010-2015; Ambassador’s Diploma, Embassy of Romania in the UK, 2009; Leverhulme Research Fellowship, 2004 – 2006; Romanian Academy “Constantin Miculescu” prize for research in Lasers and Nonlinear Optics, 1984.

Adrian Podoleanu（英国皇家工程院院士、英国物理学会与 SPIE 光学研究所院士，同时是中国光学学会国际院士）现任英国坎特伯雷肯特大学工程、数学与物理系应用光学组负责人及生物医学光学教授，兼任伦敦大学学院生物医学研究中心与英国眼科研究所研究员，并担任罗马尼亚蒂米什瓦拉大学伦敦大学学院及医学与药学院荣誉教授。他于1984年获得罗马尼亚布加勒斯特技术大学电子与电信学院电子学博士学位，是 SPIE 罗马尼亚分会的创始成员并担任首任主席（1992年）。在肯特大学任职期间，他首次获得了人眼视网膜的正面光学相干断层扫描（OCT）图像，并研发出首台OCT与扫描激光检眼镜相结合的仪器。根据Scholar GPS数据库，他终身学术排名居前列，尤其在OCT与断层扫描领域获得星级评价。目前他担任国际光学委员会副秘书长。荣誉：2017年罗马尼亚王室军官勋章；2015年皇家学会沃尔夫森研究成就奖；2010–2015年欧洲研究理事会高级研究奖学金；2009年罗马尼亚驻英国大使馆大使文凭；2004–2006年莱弗休姆研究奖学金；1984年罗马尼亚科学院“康斯坦丁·米库列斯库”激光与非线性光学研究奖。