来源: Nature Research 发布时间:2020/2/19 12:37:56
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冠状病毒研究回顾汇总 | Nature Research

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古语云温故而知新,回顾以往的研究可以帮助研究人员了解新型冠状病毒,为攻克这一难题奠定基础。自然科研精心挑选了来自Nature CommunicationsCommunications Biology以及Scientific Reports中的开放获取研究,内容涵盖冠状病毒家族的感染机制、药物发展以及疫苗研制等方向,希望为科研人员提供研究便利。

您也可以点击“阅读原文”进入Springer Nature新型冠状病毒(2019-nCoV)资源中心,及时获取与冠状病毒相关的最新研究文章,以及关于这个主题的评论文章和相关书籍。该页面上的所有内容均可免费阅读,并将不断更新。

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冠状病毒蔓延的各种因素

2018

Nature Communications

Characterizing the dynamics underlying global spread of epidemics

2017

Nature Communications

Global hotspots and correlates of emerging zoonotic diseases

2015

Scientific Reports

Inferring the hosts of coronavirus using dual statistical models based on nucleotide composition

2019

Scientific Reports

Comparative Analysis of Eleven Healthcare-Associated Outbreaks of Middle East Respiratory Syndrome Coronavirus (Mers-Cov) from 2015 to 2017

2016

Scientific Reports

The recent ancestry of Middle East respiratory syndrome coronavirus in Korea has been shaped by recombination

2019

Nature Communications

Using “outbreak science” to strengthen the use of models during epidemics

如何防止病毒蔓延的旧例

2020

Scientific Reports

Infection Prevention Measures for Surgical Procedures during a Middle East Respiratory Syndrome Outbreak in a Tertiary Care Hospital in South Korea

冠状病毒的药物发展

2020

Nature Communications

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

2015

Nature Communications

Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody

2017

Scientific Reports

Nanoparticulate vacuolar ATPase blocker exhibits potent host-targeted antiviral activity against feline coronavirus

2017

Scientific Reports

X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design

2019

Nature Communications

Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein

2017

Nature Communications

Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

2019

Nature Communications

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

2016

Scientific Reports

Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design

2018

Scientific Reports

Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis

2015

Scientific Reports

Genetic drift of human coronavirus OC43 spike gene during adaptive evolution

冠状病毒的疫苗发展

2018

Communications Biology

Evaluation of a recombination-resistant coronavirus as a broadly applicable, rapidly implementable vaccine platform

2016

Nature Communications

Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

2015

Nature Communications

Evaluation of candidate vaccine approaches for MERS-CoV

冠状病毒的感染机制

2018

Scientific Reports

Attenuation of replication by a 29 nucleotide deletion in SARS-coronavirus acquired during the early stages of human-to-human transmission

2017

Scientific Reports

Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection

2019

Nature Communications

SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

2019

Nature Communications

Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors

(来源:科学网)

 
 
 
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